Dosimetric evaluation of nuclear interaction models in the Geant4 Monte Carlo simulation toolkit for carbon-ion radiotherapy
| العنوان: | Dosimetric evaluation of nuclear interaction models in the Geant4 Monte Carlo simulation toolkit for carbon-ion radiotherapy |
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| المؤلفون: | K. Murakami, Tatsuaki Kanai, Mutsumi Tashiro, K. Amako, Nobuyuki Kanematsu, Akinori Kimura, Yuka Takei, Toshiyuki Toshito, Masataka Komori, T. Aso, Shunsuke Yonai, Satoru Kameoka, Takashi Sasaki, Go Iwai, Tomohiro Yamashita, Tatsumi Koi, H. Tomita, H. Koikegami |
| المصدر: | Radiological Physics and Technology. 1:183-187 |
| بيانات النشر: | Springer Science and Business Media LLC, 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | Nuclear reaction, Physics::Medical Physics, Monte Carlo method, Physical Therapy, Sports Therapy and Rehabilitation, Bragg peak, Models, Biological, Ion, Nuclear physics, Humans, Computer Simulation, Radiology, Nuclear Medicine and imaging, Radiometry, Nuclear Experiment, Ions, Physics, Radiation, Radiotherapy Planning, Computer-Assisted, Water, Radiotherapy Dosage, General Medicine, Carbon, Cascade, Physics::Accelerator Physics, Carbon Ion Radiotherapy, Nucleon, Monte Carlo Method, Algorithms, Beam (structure) |
| الوصف: | We tested the ability of two separate nuclear reaction models, the binary cascade and JQMD (Jaeri version of Quantum Molecular Dynamics), to predict the dose distribution in carbon-ion radiotherapy. This was done by use of a realistic simulation of the experimental irradiation of a water target. Comparison with measurement shows that the binary cascade model does a good job reproducing the spread-out Bragg peak in depth-dose distributions in water irradiated with a 290 MeV/u (per nucleon) beam. However, it significantly overestimates the peak dose for a 400 MeV/u beam. JQMD underestimates the overall dose because of a tendency to break a nucleus into lower-Z fragments than does the binary cascade model. As far as shape of the dose distribution is concerned, JQMD shows fairly good agreement with measurement for both beam energies of 290 and 400 MeV/u, which favors JQMD over the binary cascade model for the calculation of the relative dose distribution in treatment planning. |
| تدمد: | 1865-0341 1865-0333 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8caf976140ed0abdc6aa3839e16d1878 https://doi.org/10.1007/s12194-008-0026-1 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....8caf976140ed0abdc6aa3839e16d1878 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 18650341 18650333 |
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