The effect of intravenous ferric carboxymaltose on cardiac reverse remodelling following cardiac resynchronization therapy—the IRON-CRT trial
| العنوان: | The effect of intravenous ferric carboxymaltose on cardiac reverse remodelling following cardiac resynchronization therapy—the IRON-CRT trial |
|---|---|
| المؤلفون: | Pieter Martens, W.H. Wilson Tang, Paul Dendale, Pieter M. Vandervoort, Liesbeth Bruckers, Petra Nijst, Lieven Herbots, Wilfried Mullens, Jeroen Dauw, Matthias Dupont |
| المساهمون: | Bruckers, Liesbeth/0000-0002-6978-3002, Martens, Pieter/0000-0002-6036-2113, Dauw, Jeroen/0000-0003-4605-3450 |
| المصدر: | European Heart Journal. 42:4905-4914 |
| بيانات النشر: | Oxford University Press (OUP), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Cardiac function curve, medicine.medical_specialty, medicine.medical_treatment, Cardiac resynchronization therapy, Heart failure, 030204 cardiovascular system & hematology, Contractility, Ferric Compounds, Ventricular Function, Left, law.invention, Cardiac Resynchronization Therapy, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, Internal medicine, Cardiac remodelling, medicine, Clinical endpoint, Humans, 030212 general & internal medicine, Maltose, Ejection fraction, Ventricular Remodeling, business.industry, Iron deficiency, Stroke Volume, Iron Deficiencies, medicine.disease, Confidence interval, Treatment Outcome, Blood pressure, cardiovascular system, Randomized controlled trials, Cardiology, Cardiology and Cardiovascular Medicine, business |
| الوصف: | Aims Iron deficiency is common in heart failure with reduced ejection fraction (HFrEF) and negatively affects cardiac function and structure. The study the effect of ferric carboxymaltose (FCM) on cardiac reverse remodelling and contractile status in HFrEF. Methods and results Symptomatic HFrEF patients with iron deficiency and a persistently reduced left ventricular ejection fraction (LVEF Conclusions Treatment with FCM in HFrEF patients with iron deficiency and persistently reduced LVEF after CRT results in an improvement of cardiac function measured by LVEF, LVESV, and cardiac force–frequency relationship. |
| وصف الملف: | application/pdf |
| تدمد: | 1522-9645 0195-668X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d02b1fce5776744fecb6e5df072704d https://doi.org/10.1093/eurheartj/ehab411 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....8d02b1fce5776744fecb6e5df072704d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15229645 0195668X |
|---|