Energy, substrate and protein metabolism in morbid obesity before, during and after massive weight loss
| العنوان: | Energy, substrate and protein metabolism in morbid obesity before, during and after massive weight loss |
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| المؤلفون: | W.G. van Gemert, Anton J. M. Wagenmakers, P.B. Soeters, Jan Greve, D. Halliday, Klaas R. Westerterp, B.A.C. van Acker |
| المساهمون: | Algemene Heelkunde, Humane Biologie, RS: NUTRIM School of Nutrition and Translational Research in Metabolism |
| المصدر: | Scopus-Elsevier International Journal of Obesity, 24(6), 711-718. Nature Publishing Group |
| بيانات النشر: | Nature Publishing Group, 2000. |
| سنة النشر: | 2000 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Gastroplasty, Endocrinology, Diabetes and Metabolism, Protein metabolism, Medicine (miscellaneous), Doubly labeled water, Carbohydrate metabolism, Protein oxidation, Body Mass Index, chemistry.chemical_compound, Adenosine Triphosphate, Oxygen Consumption, Weight loss, Internal medicine, Weight Loss, medicine, Humans, Nutrition and Dietetics, business.industry, Protein turnover, Proteins, Middle Aged, Diet Records, Obesity, Morbid, Endocrinology, chemistry, Basal metabolic rate, Body Composition, Female, Basal Metabolism, medicine.symptom, Energy Metabolism, business, Body mass index |
| الوصف: | OBJECTIVE: To investigate the effect of surgically induced weight loss on energy, substrate and protein metabolism of morbidly obese patients. DESIGN: A prospective, clinical intervention study of morbidly obese patients before and after surgical treatment. SUBJECTS: Eight morbidly obese patients (BMI 47.88 +/- 7.03). METHODS: Total energy expenditure (TEE; doubly labeled water method), sleeping metabolic: rate (SMR; respiration chamber), body composition (deuterium oxide component of doubly labeled water), substrate metabolism (48 h dietary records, 48 h urine collection and gaseous exchange in the respiration chamber) and whole body protein turnover (primed-continuous infusion of L-[1-C-13]-leucine) were measured before, 3 and 12 months after vertical banded gastroplasty (VBG). RESULTS: The TEE decreased as a result of a decreased SMR (64%) and non-SMR (36%; P = 0.0011, SMR as a function of fat-free mass (FFM) decreased after weight loss (P |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1476-5497 0307-0565 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d60e346ebbdea29f7b530ae22fee4d3 https://doi.org/10.1038/sj.ijo.0801230 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....8d60e346ebbdea29f7b530ae22fee4d3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14765497 03070565 |
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