Anesthetic management of a patient with β-thalassemia intermedia undergoing splenectomy: a case report
| العنوان: | Anesthetic management of a patient with β-thalassemia intermedia undergoing splenectomy: a case report |
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| المؤلفون: | Takeshi Kitoh, Joe Hasegawa, Satoshi Tanaka, Koichi Ono, Tetsutaro Otagiri |
| المصدر: | Journal of Anesthesia. 19:252-256 |
| بيانات النشر: | Springer Science and Business Media LLC, 2005. |
| سنة النشر: | 2005 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Anemia, medicine.medical_treatment, Splenectomy, Hemodynamics, Anesthesia, General, Fentanyl, Hemoglobins, hemic and lymphatic diseases, Anesthesiology, medicine, Humans, Anesthesia, Isoflurane, Balanced Anesthesia, business.industry, beta-Thalassemia, medicine.disease, Blood Cell Count, Anesthesiology and Pain Medicine, Anesthetics, Inhalation, Hyperdynamic circulation, business, Anesthetics, Intravenous, medicine.drug |
| الوصف: | A 37-year-old man with beta-thalassemia intermedia (betaTI), a rare disease caused by partial or complete deficiency of beta-globin chain synthesis, fell into a hemolytic crisis. Severe anemia persisted despite frequent transfusions. Therefore, he was scheduled for splenectomy to alleviate the anemia. The preoperative laboratory data showed marked anemia and liver dysfunction. Echocardiography revealed hyperkinetic left ventricular motion and increased cardiac index (CI), indicating a compensatory hyperdynamic circulation induced by persistent, severe anemia. Our strategy during general anesthesia was to keep the hyperkinetic cardiovascular system steady. Hence, the hemodynamic parameters including the CI were measured using a Swan-Ganz catheter, and other physiological parameters were monitored perioperatively. Anesthesia was maintained with balanced anesthesia: isoflurane at low concentrations and fentanyl to avoid cardiovascular depression. Throughout the operation, vital signs were kept stable and the lactate/pyruvate ratio was unchanged, indicating that anaerobic metabolism did not increase. We report successful anesthetic management with attention to hemodynamic changes in a patient with betaTI. |
| تدمد: | 1438-8359 0913-8668 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e154c74b664bd1f174755945e9ab7c0 https://doi.org/10.1007/s00540-005-0328-y |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....8e154c74b664bd1f174755945e9ab7c0 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14388359 09138668 |
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