SERUM LEVELS OF PENICILLIN V AFTER ORAL ADMINISTRATION OF PEDIATRIC PREPARATIONS TO HEALTHY SUBJECTS
| العنوان: | SERUM LEVELS OF PENICILLIN V AFTER ORAL ADMINISTRATION OF PEDIATRIC PREPARATIONS TO HEALTHY SUBJECTS |
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| المؤلفون: | T. Midtvedt, S. Wetterhus, H. Rollag |
| المصدر: | Acta Paediatrica. 64:421-424 |
| بيانات النشر: | Wiley, 1975. |
| سنة النشر: | 1975 |
| مصطلحات موضوعية: | Adult, business.industry, High serum, Healthy subjects, Administration, Oral, Biological Availability, Physiology, General Medicine, Serum concentration, Pharmacology, Bioavailability, Penicillin, Suspensions, Oral administration, Pediatrics, Perinatology and Child Health, medicine, Humans, Penicillin V, Ingestion, Powders, business, Tablets, Biological availability, medicine.drug |
| الوصف: | The bioavailability of nine commercial pediatric preparations of penicillin V was tested in a double-blind, cross-over fashion on ten healthy student nurses who were given 1 mill I.U. of the various preparations. The serum concentrations were determined using the paper disc method of "AB Biodisc" Sweden. The preparations could be divided into two different groups: (1) the mixtures (2) the effervescent tablets, substance for drops and granulate. This classification is based upon the mean peak serum levels obtained. With one exception the peak serum levels in group 2 were significantly higher than in group 1. 2,4 and 6 hours after ingestion there were no differences in the serum levels, indicating that none of the preparations gave sustained high serum levels. The results presented indicate that the preparations in group 2 should be preferred. |
| تدمد: | 1651-2227 0803-5253 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e2e78afa6e895f850f7335eb8c5dea6 https://doi.org/10.1111/j.1651-2227.1975.tb03858.x |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....8e2e78afa6e895f850f7335eb8c5dea6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16512227 08035253 |
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