Supplementary Figure 1 from Chemotherapy Induces Intratumoral Expression of Chemokines in Cutaneous Melanoma, Favoring T-cell Infiltration and Tumor Control
التفاصيل البيبلوغرافية
العنوان:
Supplementary Figure 1 from Chemotherapy Induces Intratumoral Expression of Chemokines in Cutaneous Melanoma, Favoring T-cell Infiltration and Tumor Control
American Association for Cancer Research (AACR), 2023.
سنة النشر:
2023
الوصف:
PDF file - 782K, CD8+ T cell depletion accelerates the development of visceral tumors but has no effect on cutaneous tumors in RETAAD mice.(A) Development of visceral metastases was followed by PET scan 4 weeks and 8 weeks after initiation of the depletion of CD8+ T cells n=10 as described in (Eyles et al., 2010). Control mice n=9 were injected with rat IgG control. Data shows the percentage of mice with visceral metastases in each group. (B) Skin tumors were detected at necropsy. Data shows the number of skin tumors (left) and the percentage of mice with skin tumors (right). All data represent means � SEM. Results are representative of two independent experiments. C= control group. D= CD8 depleted. Statistical analysis was performed using Mann-Whitney U test, one-tailed.
