Cytosine arabinoside induced liver damage: Histopathologic demonstration
العنوان: | Cytosine arabinoside induced liver damage: Histopathologic demonstration |
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المؤلفون: | Ernesto Ramos, Agustin Avilés, Jesús Aguirre, J. Javier Cuenca Cervera, J Pizzuto |
المصدر: | Medical and Pediatric Oncology. 11:287-290 |
بيانات النشر: | Wiley, 1983. |
سنة النشر: | 1983 |
مصطلحات موضوعية: | Adult, Drug, Cancer Research, Pathology, medicine.medical_specialty, media_common.quotation_subject, chemistry.chemical_compound, Biopsy, medicine, Humans, Liver damage, media_common, Acute leukemia, medicine.diagnostic_test, business.industry, Cytarabine, Middle Aged, Leukemia, Myeloid, Acute, Liver, Oncology, chemistry, Pediatrics, Perinatology and Child Health, Abnormal Liver Function Test, Hepatic biopsy, Female, business, Cytosine, medicine.drug |
الوصف: | Two patients with acute leukemia developed abnormal liver function tests after the administration of cytosine arabinoside. Other possible causes for such abnormalities were not likely. In both patients a close chronologic relationship between the administration of the drug and the appearance of the laboratory abnormalities was noted. The liver damage was also documented by biopsy. To our knowledge this is the first time that the hepatotoxic effects of cytosine arabinoside are histologically demonstrated. |
تدمد: | 1096-911X 0098-1532 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f71b749b56692f526223cf9c54427f4 https://doi.org/10.1002/mpo.2950110416 |
حقوق: | CLOSED |
رقم الأكسشن: | edsair.doi.dedup.....8f71b749b56692f526223cf9c54427f4 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 1096911X 00981532 |
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