Opioid-Induced Constipation Among Patients with Chronic Noncancer Pain in the United States, Canada, Germany, and the United Kingdom: Laxative Use, Response, and Symptom Burden Over Time
| العنوان: | Opioid-Induced Constipation Among Patients with Chronic Noncancer Pain in the United States, Canada, Germany, and the United Kingdom: Laxative Use, Response, and Symptom Burden Over Time |
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| المؤلفون: | K Payne, Karen Yeomans, Soheil Chavoshi, Mary Kay Margolis, F. King, Karin S. Coyne, Robert J. LoCasale |
| المصدر: | Pain Medicine. 16:1551-1565 |
| بيانات النشر: | Oxford University Press (OUP), 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Adult, Male, Canada, medicine.medical_specialty, Longitudinal study, Constipation, medicine.medical_treatment, Laxative, Logistic regression, Naldemedine, Cost of Illness, Germany, Internal medicine, Prevalence, medicine, Humans, Longitudinal Studies, Prospective Studies, Aged, business.industry, Chronic pain, General Medicine, Middle Aged, medicine.disease, Health Surveys, Drug Utilization, United Kingdom, United States, Analgesics, Opioid, Anesthesiology and Pain Medicine, Socioeconomic Factors, Opioid, Laxatives, Quality of Life, Physical therapy, Defecation, Female, Neurology (clinical), Chronic Pain, medicine.symptom, business, medicine.drug |
| الوصف: | Purpose Estimate rate of laxative inadequate response (LIR) over time among patients with chronic noncancer pain with opioid-induced constipation (OIC). Methods A prospective longitudinal study was conducted in United States, Canada, Germany, and United Kingdom. Patients on opioid therapy for ≥4 weeks for chronic noncancer pain and OIC completed an Internet-based survey at Baseline and Weeks 2, 4, 6, 8, 12, 16, 20, and 24. 1xLIR was defined as sufficient laxative use (≥1 laxative ≥ 4 times in past 2 weeks) and inadequate response ( |
| تدمد: | 1526-4637 1526-2375 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9018ca289c576434c3e6a6f57d38c9e7 https://doi.org/10.1111/pme.12724 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....9018ca289c576434c3e6a6f57d38c9e7 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15264637 15262375 |
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