Developmental and pathological lymphangiogenesis: from models to human disease
| العنوان: | Developmental and pathological lymphangiogenesis: from models to human disease |
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| المؤلفون: | Tatiana V. Petrova, Hélène Maby-El Hajjami |
| المصدر: | Histochemistry and cell biology |
| بيانات النشر: | Springer Science and Business Media LLC, 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | Pathology, medicine.medical_specialty, Histology, Endothelium, Inflammation, Biology, Metastasis, 03 medical and health sciences, 0302 clinical medicine, Immune system, Neoplasms, medicine, Animals, Humans, Lymphedema, Lymphangiogenesis, Neoplasm Metastasis, Genetically modified animal, Molecular Biology, Cell Proliferation, Lymphatic Vessels, 030304 developmental biology, 0303 health sciences, Cell Differentiation, Cell Biology, medicine.disease, 3. Good health, Disease Models, Animal, Medical Laboratory Technology, medicine.anatomical_structure, Lymphatic system, 030220 oncology & carcinogenesis, Endothelium, Lymphatic, medicine.symptom, Neuroscience, Signal Transduction |
| الوصف: | The lymphatic vascular system, the body's second vascular system present in vertebrates, has emerged in recent years as a crucial player in normal and pathological processes. It participates in the maintenance of normal tissue fluid balance, the immune functions of cellular and antigen trafficking and absorption of fatty acids and lipid-soluble vitamins in the gut. Recent scientific discoveries have highlighted the role of lymphatic system in a number of pathologic conditions, including lymphedema, inflammatory diseases, and tumor metastasis. Development of genetically modified animal models, identification of lymphatic endothelial specific markers and regulators coupled with technological advances such as high-resolution imaging and genome-wide approaches have been instrumental in understanding the major steps controlling growth and remodeling of lymphatic vessels. This review highlights the recent insights and developments in the field of lymphatic vascular biology. |
| تدمد: | 1432-119X 0948-6143 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90579e2f356755287f3faf64317705e6 https://doi.org/10.1007/s00418-008-0525-5 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....90579e2f356755287f3faf64317705e6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1432119X 09486143 |
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