Biofilm systems as tools in biotechnological production
| العنوان: | Biofilm systems as tools in biotechnological production |
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| المؤلفون: | Miriam Edel, Harald Horn, Johannes Gescher |
| المصدر: | Applied Microbiology and Biotechnology. 103:5095-5103 |
| بيانات النشر: | Springer Science and Business Media LLC, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | 0303 health sciences, Bacteria, Polymers, 030306 microbiology, Microorganism, Biofilm, Biomass, Biofilm matrix, High cell, General Medicine, biochemical phenomena, metabolism, and nutrition, Bacterial Physiological Phenomena, Applied Microbiology and Biotechnology, Anti-Bacterial Agents, Process conditions, 03 medical and health sciences, Biofilms, Biochemical engineering, 030304 developmental biology, Biotechnology |
| الوصف: | The literature provides more and more examples of research projects that develop novel production processes based on microorganisms organized in the form of biofilms. Biofilms are aggregates of microorganisms that are attached to interfaces. These viscoelastic aggregates of cells are held together and are embedded in a matrix consisting of multiple carbohydrate polymers as well as proteins. Biofilms are characterized by a very high cell density and by a natural retentostat behavior. Both factors can contribute to high productivities and a facilitated separation of the desired end-product from the catalytic biomass. Within the biofilm matrix, stable gradients of substrates and products form, which can lead to a differentiation and adaptation of the microorganisms' physiology to the specific process conditions. Moreover, growth in a biofilm state is often accompanied by a higher resistance and resilience towards toxic or growth inhibiting substances and factors. In this short review, we summarize how biofilms can be studied and what most promising niches for their application can be. Moreover, we highlight future research directions that will accelerate the advent of productive biofilms in biology-based production processes. |
| تدمد: | 1432-0614 0175-7598 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907bcf74fa1df2962ff50ca2b66b5d22 https://doi.org/10.1007/s00253-019-09869-x |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....907bcf74fa1df2962ff50ca2b66b5d22 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14320614 01757598 |
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