Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparum
| العنوان: | Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparum |
|---|---|
| المؤلفون: | Alan Brockman, François Nosten, Jeff T. Williams, Neil French, James A. G. Whitworth, Tim J. Anderson, Marcelo U. Ferreira, Iván D. Vélez, Bernhard Haubold, Jose G. Estrada-Franco, Karen P. Day, Rene Mollinedo, John L. Mokili, Sungano Mharakurwa, Moses J. Bockarie, Lynne Richardson |
| المصدر: | Scopus-Elsevier CIÊNCIAVITAE Molecular Biology and Evolution |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Linkage disequilibrium, Genotype, Range (biology), Plasmodium falciparum, Population, Population genetics, Linkage Disequilibrium, Intraspecific competition, Evolution, Molecular, Papua New Guinea, Gene Frequency, parasitic diseases, Genetic variation, Genetics, Animals, Humans, Malaria, Falciparum, education, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Probability, education.field_of_study, Geography, biology, Genetic Variation, South America, biology.organism_classification, Biological Evolution, Evolutionary biology, Africa, Genetic structure, Plasmodium mexicanum, Microsatellite Repeats |
| الوصف: | Multilocus genotyping of microbial pathogens has revealed a range of population structures, with some bacteria showing extensive recombination and others showing almost complete clonality. The population structure of the protozoan parasite Plasmodium falciparum has been harder to evaluate, since most studies have used a limited number of antigen-encoding loci that are known to be under strong selection. We describe length variation at 12 microsatellite loci in 465 infections collected from 9 locations worldwide. These data reveal dramatic differences in parasite population structure in different locations. Strong linkage disequilibrium (LD) was observed in six of nine populations. Significant LD occurred in all locations with prevalence |
| وصف الملف: | application/octet-stream |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a62c049199c1bec04f1d84362a10c8 https://ora.ox.ac.uk/objects/uuid:ad7feb51-887f-4e73-8c15-cae5d7b77584 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....90a62c049199c1bec04f1d84362a10c8 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |