Reparative and Regenerative Effects of Mesenchymal Stromal Cells—Promising Potential for Kidney Transplantation?
| العنوان: | Reparative and Regenerative Effects of Mesenchymal Stromal Cells—Promising Potential for Kidney Transplantation? |
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| المؤلفون: | Merel B F Pool, Cyril Moers, Henri G. D. Leuvenink |
| المصدر: | International Journal of Molecular Sciences International Journal of Molecular Sciences, Vol 20, Iss 18, p 4614 (2019) |
| بيانات النشر: | MDPI, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | RENAL-FUNCTION, DIFFERENTIATION CAPACITY, BONE-MARROW, kidney transplantation, Review, Mesenchymal Stem Cell Transplantation, Regenerative Medicine, Kidney transplant, Catalysis, Inorganic Chemistry, lcsh:Chemistry, Immunomodulation, VERSUS-HOST-DISEASE, Medicine, Animals, Humans, ALLOGRAFT-REJECTION, Physical and Theoretical Chemistry, Molecular Biology, lcsh:QH301-705.5, Spectroscopy, Kidney transplantation, Wound Healing, business.industry, Regeneration (biology), Organic Chemistry, Mesenchymal stem cell, Mesenchymal Stem Cells, General Medicine, Acute Kidney Injury, medicine.disease, Computer Science Applications, Transplantation, RAT-KIDNEY, medicine.anatomical_structure, ADIPOSE-TISSUE, Treatment Outcome, lcsh:Biology (General), lcsh:QD1-999, Allograft rejection, regeneration, Cancer research, UMBILICAL-CORD BLOOD, Bone marrow, Stem cell, SPINAL-CORD, business, mesenchymal stromal cells, STEM-CELLS |
| الوصف: | Mesenchymal stromal cells (MSCs) possess reparative, regenerative and immunomodulatory properties. The current literature suggests that MSCs could improve kidney transplant outcome via immunomodulation. In many clinical domains, research has also focussed on the regenerative and reparative effects of therapies with MSCs. However, in the field of transplantation, data on this subject remain scarce. This review provides an overview of what is known about the regenerative and reparative effects of MSCs in various fields ranging from wound care to fracture healing and also examines the potential of these promising MSC properties to improve the outcome of kidney transplantations. |
| اللغة: | English |
| تدمد: | 1422-0067 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913fd8e1bfa169a97852df49a9bceade http://europepmc.org/articles/PMC6770554 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....913fd8e1bfa169a97852df49a9bceade |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14220067 |
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