Near Elimination of Hepatitis B Virus Infections Among Hawaii Elementary School Children After Universal Infant Hepatitis B Vaccination
| العنوان: | Near Elimination of Hepatitis B Virus Infections Among Hawaii Elementary School Children After Universal Infant Hepatitis B Vaccination |
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| المؤلفون: | Anthony E. Fiore, Wendi L. Kuhnert, Janice I. Huggler, Joe L. Elm, Paul V. Effler, Joseph F. Perz |
| المصدر: | Pediatrics. 118:1403-1408 |
| بيانات النشر: | American Academy of Pediatrics (AAP), 2006. |
| سنة النشر: | 2006 |
| مصطلحات موضوعية: | Male, Pediatrics, medicine.medical_specialty, Population, medicine.disease_cause, Hawaii, Orthohepadnavirus, Seroepidemiologic Studies, medicine, Humans, Hepatitis B Vaccines, Child, education, Hepatitis B virus, education.field_of_study, biology, Immunization Programs, business.industry, Health Policy, Incidence, Incidence (epidemiology), Hepatitis B, medicine.disease, biology.organism_classification, Vaccination, Cross-Sectional Studies, Hepadnaviridae, Pediatrics, Perinatology and Child Health, Immunology, Female, Viral disease, business, Follow-Up Studies |
| الوصف: | OBJECTIVES. Hawaii implemented routine infant hepatitis B vaccination in 1992 and required it for school entry in 1997. Previously, in 1989, a serologic survey among Hawaii school children in grades 1 to 3 indicated that 1.6% had chronic hepatitis B virus infection, and 2.1% had resolved infection. We conducted a follow-up survey to examine changes in hepatitis B virus infection rates.PATIENTS AND METHODS. This study was performed in Oahu, Hawaii, during the 2001–2002 school year among children in grades 2 and 3. Consenting parents/guardians provided demographic information including place of birth. Participants were tested for serologic evidence of hepatitis B virus infection and their vaccination status was determined by reviewing school records. Rates of symptomatic acute hepatitis B among persons aged ≤19 years were calculated from cases reported from Hawaii to the Centers for Disease Control and Prevention between 1990 and 2004.RESULTS. Completed hepatitis B vaccination series were documented for 83% of the 2469 participants by age 18 months and for 97% by age 5 years. Past or present hepatitis B virus infection was detected among 6 participants (0.24%), including 1 (0.04%) with chronic infection and 5 (0.20%) with resolved infections. Compared with the 1989 survey, these prevalences represent declines of 97% and 90% in chronic and resolved hepatitis B virus infections, respectively. The incidence of symptomatic acute hepatitis B in Hawaii children and adolescents aged ≤19 years decreased from 4.5 cases per 100000 in 1990 to 0.0 during 2002–2004. To date, the last reported case in a child aged CONCLUSIONS.. Hepatitis B virus infection has nearly been eliminated in Hawaii children born after universal infant hepatitis B vaccination was implemented. These findings suggest that hepatitis B prevention goals are being met through routine immunization and related prevention programs among US children. |
| تدمد: | 1098-4275 0031-4005 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91785e3eeca9e6c24c7c2bc4b86c5a98 https://doi.org/10.1542/peds.2006-0724 |
| رقم الأكسشن: | edsair.doi.dedup.....91785e3eeca9e6c24c7c2bc4b86c5a98 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10984275 00314005 |
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