Angio-TC pulmonar durante la pandemia de COVID-19: comparación en pacientes con y sin la infección y con una serie prepandémica
| العنوان: | Angio-TC pulmonar durante la pandemia de COVID-19: comparación en pacientes con y sin la infección y con una serie prepandémica |
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| المؤلفون: | J.M. Castro-García, J.J. Arenas-Jiménez, A. Ureña-Vacas, E. García-Garrigós, P. Sirera-Sirera |
| المصدر: | Radiologia r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante instname |
| بيانات النشر: | Elsevier BV, 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | pulmonary embolism, COVID-19, Radiology, Nuclear Medicine and imaging, fibrinogen degradation products |
| الوصف: | BACKGROUND AND AIMS: To analyze the diagnostic performance of pulmonary CT angiography and to compare different D-dimer cutoffs for the diagnosis of acute pulmonary embolism in patients with and without SARS-CoV-2 infections. MATERIALS AND METHODS: We retrospectively analyzed all consecutive pulmonary CT angiography studies done for suspected pulmonary embolism in a tertiary hospital during two time periods: the first December 2020 through February 2021 and the second December 2017 through February 2018.D-dimer levels were obtained less than 24 hours before the pulmonary CT angiography studies. We analyzed the sensitivity, specificity, positive and negative predictive values, area under the receiver operating curve (AUC), and pattern of pulmonary embolism for six different values of D-dimer and the extent of the embolism. During the pandemic period, we also analyzed whether the patients had COVID-19. RESULTS: After excluding 29 poor-quality studies, 492 studies were analyzed; 352 of these were done during the pandemic, 180 in patients with COVID-19 and 172 in patients without COVID-19.The absolute frequency of pulmonary embolism diagnosed was higher during the pandemic period (34 cases during the prior period and 85 during the pandemic; 47 of these patients had COVID-19). No significant differences were found in comparing the AUCs for the D-dimer values. The optimum values calculated for the receiver operating characteristic curves differed between patients with COVID-19 (2200 mcg/L), without COVID-19 (4800 mcg/L), and diagnosed in the prepandemic period (3200 mcg/L).Peripheral distribution of the emboli was more common in patients with COVID-19 (72%) than in those without COVID-19 and than in those diagnosed before the pandemic [OR 6.6, 95% CI:1.5?24.6, p |
| تدمد: | 0033-8338 1578-178X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9191a3dc3f3ff16ebf74247dbd737b4a https://doi.org/10.1016/j.rx.2022.07.005 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....9191a3dc3f3ff16ebf74247dbd737b4a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 00338338 1578178X |
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