أعرض في EDS

Monochorionic-triamniotic triplet pregnancy after intracytoplasmic sperm injection, assisted hatching, and two-embryo transfer: first reported case following IVF

التفاصيل البيبلوغرافية
العنوان: Monochorionic-triamniotic triplet pregnancy after intracytoplasmic sperm injection, assisted hatching, and two-embryo transfer: first reported case following IVF
المؤلفون: Julie H Zimmermann, Daniel P Eller, Mark Perloe, E Scott Sills, Michael J. Tucker, Labib M. Ghulmiyyah
المصدر: BMC Pregnancy and Childbirth, Vol 3, Iss 1, p 4 (2003)
BMC Pregnancy and Childbirth
بيانات النشر: BMC, 2003.
سنة النشر: 2003
مصطلحات موضوعية: Gynecology, medicine.medical_specialty, Pregnancy, animal structures, In vitro fertilisation, Maternal and child health, business.industry, medicine.medical_treatment, Reproductive medicine, Obstetrics and Gynecology, Case Report, medicine.disease, lcsh:Gynecology and obstetrics, Intracytoplasmic sperm injection, Embryo transfer, Andrology, Assisted hatching, Obstetrics and Gynaecology, embryonic structures, medicine, Triplet Pregnancy, triplet pregnancy / IVF / monochorionic / cerclage / outcome, business, reproductive and urinary physiology, lcsh:RG1-991
الوصف: Background We present a case of monochorionic-triamniotic pregnancy that developed after embryo transfer following in vitro fertilization (IVF). Methods After controlled ovarian hyperstimulation and transvaginal retrieval of 22 metaphase II oocytes, fertilization was accomplished with intracytoplasmic sperm injection (ICSI). Assisted embryo hatching was performed, and two embryos were transferred in utero. One non-transferred blastocyst was cryopreserved. Results Fourteen days post-transfer, serum hCG level was 423 mIU/ml and subsequent transvaginal ultrasound revealed a single intrauterine gestational sac with three separate amnion compartments. Three distinct foci of cardiac motion were detected and the diagnosis was revised to monochorionic-triamniotic triplet pregnancy. Antenatal management included cerclage placement at 19 weeks gestation and hospital admission at 28 weeks gestation due to mild preeclampsia. Three viable female infants were delivered via cesarean at 30 5/7 weeks gestation. Conclusions The incidence of triplet delivery in humans is approximately 1:6400, and such pregnancies are classified as high-risk for reasons described in this report. We also outline an obstetric management strategy designed to optimize outcomes. The roles of IVF, ICSI, assisted embryo hatching and associated laboratory culture conditions on the subsequent development of monozygotic/monochorionic pregnancy remain controversial. As demonstrated here, even when two-embryo transfer is employed after IVF the statistical probability of monozygotic multiple gestation cannot be reduced to zero. We encourage discussion of this possibility during informed consent for the advanced reproductive technologies.
اللغة: English
تدمد: 1471-2393
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b33092dd4a9ff97d96ca2e1b9661c0
http://www.biomedcentral.com/1471-2393/3/4
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....92b33092dd4a9ff97d96ca2e1b9661c0
قاعدة البيانات: OpenAIRE
الوصف
تدمد:14712393