التفاصيل البيبلوغرافية
العنوان:
Novel Steroidal Vinyl Fluorides as Inhibitors of Steroid C17(20) Lyase
المؤلفون:
Robert J. Resvick , Dirk Friedrich , Norton P. Peet , Burkhart Joseph P , Roy J. Vaz , Philippe Bey , Cynthia A. Gates , Philip M. Weintraub , Angelastro Michael R
المصدر:
Bioorganic & Medicinal Chemistry . 10:929-934
بيانات النشر:
Elsevier BV, 2002.
سنة النشر:
2002
مصطلحات موضوعية:
Vinyl Compounds , Stereochemistry , medicine.medical_treatment , Clinical Biochemistry , Pharmaceutical Science , Biochemistry , Chemical synthesis , Steroid , Structure-Activity Relationship , chemistry.chemical_compound , Drug Discovery , medicine , Animals , Enzyme Inhibitors , Molecular Biology , chemistry.chemical_classification , Dose-Response Relationship, Drug , biology , Chemistry , Organic Chemistry , Steroid 17-alpha-Hydroxylase , Lyase , Enol , In vitro , Macaca fascicularis , Enzyme , Enzyme inhibitor , Pregnenolone , biology.protein , Molecular Medicine , Steroids, Fluorinated , medicine.drug
الوصف:
20-Fluoro-17(20)-pregnenolone derivatives were designed as enol mimics of pregnenolone. All of the targeted, novel fluoroolefins were potent inhibitors of C 17(20) lyase.
تدمد:
0968-0896
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9321fff6a0512a06daafdc2bb55e987e https://doi.org/10.1016/s0968-0896 (01)00354-6
حقوق:
CLOSED
رقم الأكسشن:
edsair.doi.dedup.....9321fff6a0512a06daafdc2bb55e987e
قاعدة البيانات:
OpenAIRE
