Association of Metabolic Syndrome with COVID-19 in the Republic of Korea

التفاصيل البيبلوغرافية
العنوان: Association of Metabolic Syndrome with COVID-19 in the Republic of Korea
المؤلفون: In-Hwan Oh, So-Youn Park, Woo-Hwi Jeon, Jeong-Yeon Seon
المصدر: Diabetes & Metabolism Journal. 46:427-438
بيانات النشر: Korean Diabetes Association, 2022.
سنة النشر: 2022
مصطلحات موضوعية: Male, Metabolic Syndrome, medicine.medical_specialty, Waist, business.industry, Endocrinology, Diabetes and Metabolism, COVID-19, Odds ratio, medicine.disease, Logistic regression, Confidence interval, Risk Factors, Diabetes mellitus, Internal medicine, Epidemiology, Odds Ratio, medicine, Humans, Female, Waist Circumference, Metabolic syndrome, Risk factor, business
الوصف: Background: Metabolic syndrome (MetS) is reportedly a crucial risk factor for coronavirus disease 2019 (COVID-19). Since the epidemiological studies that examine this association are few and include small samples, we investigated the relationship between MetS and COVID-19 severity and death using a larger sample in the Republic of Korea.Methods: We analyzed 66,321 patients, 4,066 of whom had COVID-19. We used chi-square tests to examine patients’ characteristics. We performed logistic regression analysis to analyze differences in COVID-19 infection and clinical outcomes according to the presence of MetS.Results: Although MetS was not significantly associated with COVID-19 risk, acquiring MetS was significantly associated with the risk of severe COVID-19 outcomes (odds ratio [OR], 1.97; 95% confidence interval [CI], 1.34 to 2.91; P=0.001). The mortality risk was significantly higher in COVID-19 patients with MetS (OR, 1.74; 95% CI, 1.17 to 2.59; P=0.006). Patients with abnormal waist circumference were approximately 2.07 times more likely to develop severe COVID-19 (PP=0.012).Conclusion: COVID-19 is likely associated with severity and death in patients with MetS or in patients with MetS risk factors. Therefore, patients with MetS or those with abnormal waist circumference and HDL-C levels need to be treated with caution.
تدمد: 2233-6087
2233-6079
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939a09dc629f05178f978474f228c2b4
https://doi.org/10.4093/dmj.2021.0105
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....939a09dc629f05178f978474f228c2b4
قاعدة البيانات: OpenAIRE