أعرض في EDS

Artificial Food Colors and Attention-Deficit/Hyperactivity Symptoms: Conclusions to Dye for

التفاصيل البيبلوغرافية
العنوان: Artificial Food Colors and Attention-Deficit/Hyperactivity Symptoms: Conclusions to Dye for
المؤلفون: L. Eugene Arnold, Elizabeth Hurt, Nicholas Lofthouse
المصدر: Neurotherapeutics. 9:599-609
بيانات النشر: Springer Science and Business Media LLC, 2012.
سنة النشر: 2012
مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Blinding, United States Food and Drug Administration, Advisory committee, Public health, Genetic vulnerability, MEDLINE, Food Coloring Agents, History, 20th Century, Affect (psychology), Article, United States, Developmental psychology, Attention Deficit Disorder with Hyperactivity, medicine, Attention deficit, Humans, Pharmacology (medical), Neurology (clinical), Psychology, Classroom climate
الوصف: The effect of artificial food colors (AFCs) on child behavior has been studied for more than 35 years, with accumulating evidence from imperfect studies. This article summarizes the history of this controversial topic and testimony to the 2011 Food and Drug Administration Food Advisory Committee convened to evaluate the current status of evidence regarding attention-deficit/hyperactivity disorder (ADHD). Features of ADHD relevant to understanding the AFC literature are explained: ADHD is a quantitative diagnosis, like hypertension, and some individuals near the threshold may be pushed over it by a small symptom increment. The chronicity and pervasiveness make caregiver ratings the most valid measure, albeit subjective. Flaws in many studies include nonstandardized diagnosis, questionable sample selection, imperfect blinding, and nonstandardized outcome measures. Recent data suggest a small but significant deleterious effect of AFCs on children's behavior that is not confined to those with diagnosable ADHD. AFCs appear to be more of a public health problem than an ADHD problem. AFCs are not a major cause of ADHD per se, but seem to affect children regardless of whether or not they have ADHD, and they may have an aggregated effect on classroom climate if most children in the class suffer a small behavioral decrement with additive or synergistic effects. Possible biological mechanisms with published evidence include the effects on nutrient levels, genetic vulnerability, and changes in electroencephalographic beta-band power. A table clarifying the Food and Drug Administration and international naming systems for AFCs, with cross-referencing, is provided.
تدمد: 1878-7479
1933-7213
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9642f5211d5ec100a085222e1ce01639
https://doi.org/10.1007/s13311-012-0133-x
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....9642f5211d5ec100a085222e1ce01639
قاعدة البيانات: OpenAIRE
الوصف
تدمد:18787479
19337213