Dissociation of Cross-Sectional Trajectories for Verbal and Visuo-Spatial Working Memory Development in Rubinstein-Taybi Syndrome
| العنوان: | Dissociation of Cross-Sectional Trajectories for Verbal and Visuo-Spatial Working Memory Development in Rubinstein-Taybi Syndrome |
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| المؤلفون: | Sarah R. Beck, Laurie Powis, Jane Waite, Mary Heald, Chris Oliver |
| المصدر: | Journal of Autism and Developmental Disorders |
| بيانات النشر: | Springer US, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Typically developing children, Adult, Male, Rubinstein–Taybi syndrome, Adolescent, Spatial ability, Short-term memory, Verbal learning, Spatial memory, behavioral disciplines and activities, 03 medical and health sciences, Young Adult, 0302 clinical medicine, parasitic diseases, Developmental and Educational Psychology, Humans, 0501 psychology and cognitive sciences, Child, Mental age, Rubinstein-Taybi Syndrome, Original Paper, Memory Disorders, Working memory, musculoskeletal, neural, and ocular physiology, 05 social sciences, Cognition, Verbal Learning, Vineland Adaptive Behavior Scale, Cross-Sectional Studies, Memory, Short-Term, Child, Preschool, Female, Psychology, 030217 neurology & neurosurgery, psychological phenomena and processes, Dissociation, 050104 developmental & child psychology, Cognitive psychology |
| الوصف: | Working memory (WM) impairments might amplify behavioural difference in genetic syndromes. Murine models of Rubinstein-Taybi syndrome (RTS) evidence memory impairments but there is limited research on memory in RTS. Individuals with RTS and typically developing children completed WM tasks, with participants with RTS completing an IQ assessment and parents/carers completing the Vineland Adaptive Behavior Scales. A cross-sectional trajectory analysis was conducted. There were significant WM span deficits in RTS relative to mental age. Verbal WM span was positively associated with mental age; however, this was not observed for visuo-spatial span. There is a dissociation between WM domains in RTS. Individuals may have difficulties with tasks relying on WM span, above difficulties predicted by overall ability. |
| اللغة: | English |
| تدمد: | 1573-3432 0162-3257 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b10da9484d3d9fadcfb88e169434d2 http://europepmc.org/articles/PMC4860195 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....96b10da9484d3d9fadcfb88e169434d2 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 15733432 01623257 |
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