What size cutoff level should be used to implement optical polyp diagnosis?
| العنوان: | What size cutoff level should be used to implement optical polyp diagnosis? |
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| المؤلفون: | Mahsa Taghiakbari, Heiko Pohl, Roupen Djinbachian, Joseph C. Anderson, Danny Metellus, Alan N. Barkun, Mickael Bouin, Daniel von Renteln |
| المصدر: | Endoscopy. 54:1182-1190 |
| بيانات النشر: | Georg Thieme Verlag KG, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Male, Adenoma, Gastroenterology, Humans, Colonic Polyps, Mass Screening, Female, Prospective Studies, Colonoscopy, Colorectal Neoplasms, Aged |
| الوصف: | Background The risk of advanced pathology increases with polyp size, as does the potential for mismanagement when optical diagnosis is used. This study aimed to evaluate the proportion of patients who would be assigned inadequate surveillance intervals when different size cutoffs are adopted for use of optical diagnosis. Methods In a post hoc analysis of three prospective studies, the use of optical diagnosis was evaluated for three polyp size groups: 1–3, 1–5, and 1–10 mm. The primary outcome was the proportion of patients in whom advanced adenomas were found and optical diagnosis resulted in delayed surveillance. Secondary outcomes included agreements between surveillance intervals based on high confidence optical diagnosis and pathology outcomes, reduction in histopathological examinations, and proportion of patients who could receive an immediate surveillance recommendation. Results We included 3374 patients (7291 polyps ≤ 10 mm) undergoing complete colonoscopies (median age 66.0 years, 75.2 % male, 29.6 % for screening). The percentage of patients with advanced adenomas and either 2- or 7-year delayed surveillance intervals (n = 79) was 3.8 %, 15.2 %, and 25.3 % for size cutoffs of 1–3, 1–5, and 1–10 mm polyps, respectively (P Conclusion A 3-mm cutoff for clinical implementation of optical diagnosis resulted in a very low risk of delayed management of advanced neoplasia while showing high surveillance interval agreement with pathology and a one-third reduction in overall requirement for pathology examinations. |
| تدمد: | 1438-8812 0013-726X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96fdad3cbbaf241ddfa376f0664c1d6e https://doi.org/10.1055/a-1843-9535 |
| رقم الأكسشن: | edsair.doi.dedup.....96fdad3cbbaf241ddfa376f0664c1d6e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14388812 0013726X |
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