MRI of the live fish brain at 3 Tesla: Feasibility, technique and interspecies anatomic variations
| العنوان: | MRI of the live fish brain at 3 Tesla: Feasibility, technique and interspecies anatomic variations |
|---|---|
| المؤلفون: | Jennifer R. Clark, Alvin C. Camus, Jessica Comolli, Stephen J. Divers, Karine P. Gendron |
| المصدر: | Veterinary Radiology & Ultrasound. 64:75-85 |
| بيانات النشر: | Wiley, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | General Veterinary |
| الوصف: | Advances in aquatic animal medicine and continued growth of the fish hobbyist and aquaculture communities have led to a developing interest in antemortem diagnostic imaging of aquatic species. The aims of this prospective, pilot study were to determine whether advanced neuroimaging can be safely achieved in live fish using clinically available equipment, to optimize imaging parameters, and to develop a comparative MRI atlas of a few fish species of economic or research value. Two each of channel catfish (Ictalurus punctatus), koi (Cyprinus rubrofuscus), and grass carp (Ctenopharyngodon idella) of at least 30 cm in length were individually anesthetized for 3 Tesla (3T) magnetic resonance imaging (MRI) of the brain. All fish achieved an adequate anesthetic level for prolonged immobilization during imaging. Diagnostic quality images were obtained for all subjects; however, the spatial resolution was maximized with larger fish. Imaging protocols were optimized for standard neuroimaging sequences. Additionally, inversion times for fluid-attenuation inversion recovery (FLAIR) sequences were adapted to the naturally high protein content of fish pericerebral fluid. Following imaging, the fish successfully recovered from anesthesia, were humanely euthanized, and were immediately processed to assess brain histopathology. Necropsy confirmed the sex and health status of each fish. A limited comparative MRI atlas was created of the brains of these species for clinical reference. Findings from the current study supported the use of 3T MRI as an adjunct diagnostic test for fish with suspected neurologic disease and provided a limited anatomic atlas of the teleost brain for use as a reference. |
| تدمد: | 1740-8261 1058-8183 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a394d2579343bfc799db82b73d44226 https://doi.org/10.1111/vru.13128 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....9a394d2579343bfc799db82b73d44226 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17408261 10588183 |
|---|