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LAMMER Kinase Lkh1 Is an Upstream Regulator of Prk1-Mediated Non-Sexual Flocculation in Fission Yeast

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العنوان: LAMMER Kinase Lkh1 Is an Upstream Regulator of Prk1-Mediated Non-Sexual Flocculation in Fission Yeast
المؤلفون: Kyung Sook Bae, Soo Jeong Kwon, Yoon-Dong Park, Hee-Moon Park
المصدر: Mycobiology
Mycobiology, Vol 46, Iss 3, Pp 236-241 (2018)
بيانات النشر: Informa UK Limited, 2018.
سنة النشر: 2018
مصطلحات موضوعية: 0301 basic medicine, Flocculation, 030106 microbiology, Lkh1, Regulator, Biology, Microbiology, 03 medical and health sciences, LAMMER kinase, lcsh:Botany, negative regulator, Gene, Sexual flocculation, Kinase, Non-sexual flocculation, Prk1, biology.organism_classification, Phenotype, Yeast, lcsh:QK1-989, Cell biology, 030104 developmental biology, Infectious Diseases, Schizosaccharomyces pombe, Research Article
الوصف: The cation-dependent galactose-specific flocculation activity of the Schizosaccharomyces pombe null mutant of lkh1+, the gene encoding LAMMER kinase homolog, has previously been reported by our group. Here, we show that disruption of prk1+, another flocculation associated regulatory kinase encoding gene, also resulted in cation-dependent galactose-specific flocculation. Deletion of prk1 increased the flocculation phenotype of the lkh1+ null mutant and its overexpression reversed the flocculation of cells caused by lkh1 deletion. Transcript levels of prk1+ were also decreased by lkh1+ deletion. Cumulatively, these results indicate that Lkh1 is one of the negative regulators acting upstream of Prk1, regulating non-sexual flocculation in fission yeast.
تدمد: 2092-9323
1229-8093
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a56e967c5d66c789f428be7fe382286
https://doi.org/10.1080/12298093.2018.1513115
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....9a56e967c5d66c789f428be7fe382286
قاعدة البيانات: OpenAIRE
الوصف
تدمد:20929323
12298093