Melting transition of oriented Li-DNA fibers submerged in ethanol solutions
| العنوان: | Melting transition of oriented Li-DNA fibers submerged in ethanol solutions |
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| المؤلفون: | Viviana Cristiglio, Michel Peyrard, Gaël Moiroux, Santiago Cuesta-Lopez, Adrián González, Estelle Mossou, Nikos Theodorakopoulos, Jean-Luc Garden, Andrew Wildes |
| المساهمون: | Institut Laue-Langevin (ILL), Epitaxie et couches minces (NEEL- EpiCM), Institut Néel (NEEL), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Universidad de Burgos, Universität Konstanz, Département de Physique [ENS Lyon], École normale supérieure de Lyon (ENS de Lyon)-Université de Lyon |
| المصدر: | Biopolymers Biopolymers, 2021, 112 (3), pp.e23422. ⟨10.1002/bip.23422⟩ |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Models, Molecular, Base pair, Neutron diffraction, Biophysics, Analytical chemistry, Calorimetry, 010402 general chemistry, Nucleic Acid Denaturation, 01 natural sciences, Biochemistry, Phase Transition, Biomaterials, Nucleic acid thermodynamics, chemistry.chemical_compound, Scattering, Small Angle, Transition Temperature, [PHYS]Physics [physics], Aqueous solution, Ethanol, Transition (genetics), 010405 organic chemistry, Chemistry, Organic Chemistry, Water, General Medicine, DNA, 0104 chemical sciences, Solutions, Neutron Diffraction, Nucleic Acid Conformation, Thermodynamics |
| الوصف: | International audience; The melting transition of Li-DNA fibers immersed in ethanol-water solutions has been studied using calorimetry and neutron diffraction techniques. The data have been analyzed using the Peyrard-Bishop-Dauxois model to determine the strengths of the intra- and inter-base pair potentials. The data and analysis show that the potentials are weaker than those for DNA in water. They become weaker still and the DNA less stable as the ethanol concentration increases but, conversely, the fibers become more compact and the distances between base pairs become more regular. The results show that the melting transition is relatively insensitive to local confinement and depends more on the interaction between the DNA and its aqueous environment. |
| تدمد: | 1097-0282 0006-3525 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b10d1226f5f0e9849a259988aef503e https://pubmed.ncbi.nlm.nih.gov/33600618 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....9b10d1226f5f0e9849a259988aef503e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10970282 00063525 |
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