التفاصيل البيبلوغرافية
العنوان:
Repurposing the Damage Repair Protein Methyl Guanine Methyl Transferase as a Ligand Inducible Fusion Degron
المؤلفون:
Murawska, Gosia M. , Vogel, Caspar , Jan, Max , Lu, Xinyan , Schild, Matthias , Slabicki, Mikolaj , Zou, Charles , Zhanybekova, Saule , Manojkumar, Manisha , Petzold, Georg , Kaiser, Peter , Thomä, Nicolas , Ebert, Benjamin , Gillingham, Dennis
المصدر:
ACS Chemical Biology
سنة النشر:
2022
مصطلحات موضوعية:
DNA Repair Enzymes , DNA Repair , Tumor Suppressor Proteins , Humans , Molecular Medicine , General Medicine , CRISPR-Cas Systems , Ligands , DNA Modification Methylases , Biochemistry , Cell Line , DNA Damage
الوصف:
We successfully repurpose the DNA repair protein methylguanine methyltransferase (MGMT) as an inducible degron for protein fusions. MGMT is a suicide protein that removes alkyl groups from the O
تدمد:
1554-8929
DOI:
10.1021/acschembio.1c00771
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b5445cb6cd7f7b9998e5ff6552757bd
حقوق:
OPEN
رقم الأكسشن:
edsair.doi.dedup.....9b5445cb6cd7f7b9998e5ff6552757bd
قاعدة البيانات:
OpenAIRE
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