Preoperative Controlling Nutritional Status (CONUT) score predicts short-term outcomes of patients with gastric cancer after laparoscopy-assisted radical gastrectomy
| العنوان: | Preoperative Controlling Nutritional Status (CONUT) score predicts short-term outcomes of patients with gastric cancer after laparoscopy-assisted radical gastrectomy |
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| المؤلفون: | Xiaolong Ge, Wei Zhou, Wei-hua Yu, Jiemin Lv, Xian-Fa Wang, Junhai Pan, Jia-Qi Gao, Yun Qian, Jia-Fei Yan, Huaying Liu |
| المصدر: | World Journal of Surgical Oncology World Journal of Surgical Oncology, Vol 19, Iss 1, Pp 1-10 (2021) |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Laparoscopic surgery, medicine.medical_specialty, Multivariate analysis, medicine.medical_treatment, Youden's J statistic, lcsh:Surgery, Nutritional Status, lcsh:RC254-282, Postoperative complications, Gastrectomy, Stomach Neoplasms, Surgical oncology, medicine, Humans, Controlling Nutritional Status score, Laparoscopy, Retrospective Studies, medicine.diagnostic_test, business.industry, Research, Incidence (epidemiology), Area under the curve, lcsh:RD1-811, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Prognosis, Surgery, Oncology, Gastric cancer, business |
| الوصف: | Background An emerging prediction tool, the Controlling Nutritional Status (CONUT) score, has shown good assessment ability of postoperative outcomes in cancer patients. This study evaluated the role of the preoperative CONUT score regarding the short-term outcomes of gastric cancer (GC) after laparoscopic gastrectomy. Methods Three hundred and nine GC patients undergoing laparoscopic gastrectomy from January 2016 to June 2019 were analysed, retrospectively. The patients were divided into two groups according to the CONUT optimal cut-off value. Clinical characteristics and postoperative complications in the two groups were analysed and evaluated. Risk factors for complications were identified by univariate and multivariate analyses. Results A total of 309 patients underwent laparoscopic gastrectomy; 91 (29.4%) patients experienced postoperative complications. The preoperative CONUT score showed a good predictive ability for postoperative complications (area under the curve (AUC) = 0.718, Youden index = 0.343) compared with other indices, with an optimal cut-off value of 2.5. Patients with high CONUT score had a significantly higher incidence of overall complications (P < 0.001). Age, haemoglobin, C-reactive protein, red blood cell levels, CONUT scores, surgical procedure type, T1, T4, N0 and N3 pathological TNM classification, and pathological stages of I and III were associated with postoperative complications (P < 0.05). Furthermore, the preoperative CONUT score was identified as an independent risk predictor of postoperative complications (P = 0.012; OR = 2.433; 95% CI, 1.218-4.862) after multivariate analysis. Conclusions The preoperative CONUT score is a practical nutritional assessment for predicting short-term outcomes in GC patients after laparoscopy-assisted gastrectomy. |
| تدمد: | 1477-7819 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c49d92c779bd9035e5969c9e3528088 https://doi.org/10.1186/s12957-021-02132-6 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....9c49d92c779bd9035e5969c9e3528088 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14777819 |
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