Previously published ethno-pharmacological reports reveal the potentiality of plants and plant-derived products used as traditional home remedies by Bangladeshi COVID-19 patients to combat SARS-CoV-2
| العنوان: | Previously published ethno-pharmacological reports reveal the potentiality of plants and plant-derived products used as traditional home remedies by Bangladeshi COVID-19 patients to combat SARS-CoV-2 |
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| المؤلفون: | A T M Rafiqul Islam, Jannatul Ferdousi, Shahinozzaman |
| المصدر: | Saudi Journal of Biological Sciences Saudi Journal of Biological Sciences, Vol 28, Iss 11, Pp 6653-6673 (2021) |
| بيانات النشر: | Elsevier BV, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Ethnobotany, HEp-2 cells, Epithelial cells of human larynx carcinoma, H1N1, Hemagglutinin Type 1 and Neuraminidase Type 1, HLAC, Human lymphoid aggregate cultures, MDCK, Madin-Darby Canine Kidney cell lines, MCP-1, Monocyte chemoattractant protein-1, Sore throat, IL, Interleukin, SARS, Severe acute respiratory syndrome, MERS, Middle East respiratory syndrome, Biology (General), Medicinal plants, Huh-7, Human hepatocyte-derived carcinoma cell line, Bangladesh, Traditional medicine, food and beverages, ICU, Intensive care unit, TNF-β, Tumor necrosis factor‐beta, FRhk-4cells, Fetal rhesus monkey kidney cells, IBD, Inflammatory bowel disease, Original Article, Chills, MARC-145 cells, African green monkey kidney cell line, medicine.symptom, General Agricultural and Biological Sciences, BAL, Bronchoalveolar lavage, VERO cell lines, African green monkey kidney cell lines, Coronavirus disease 2019 (COVID-19), QH301-705.5, Traditional home remedies, TNF‐α, Tumor necrosis factor‐alpha, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), HeLa, Human epithelial cervical carcinoma cell lines, COPD, Chronic obstructive pulmonary disease, NF-κB, Nuclear factor-kappaB, CHO-K1, Wild-type Chinese hamster ovary CHO-K1 cells, CIK, Ctenopharyngodon idellus kidney Cell line, BALF, Bronchoalveolar lavage fluid, medicine, CRFK, Crandell-Reese feline kidney cells, EPO, Eosinophil peroxidase, Home Remedies, EGCG, Epigallocatechin-3-gallate, ComputingMethodologies_COMPUTERGRAPHICS, Th, T-helper, Asthma, CRD, Complex chronic respiratory disease, business.industry, COVID-19, RT-PCR, Reverse transcription polymerase chain reaction, medicine.disease, HEK293T, Human embryonic kidney cells, IFN‐γ, Interferon‐gamma, IgE, Immunoglobulin E, MEF, Mouse embryonic fibroblast cells, PBMCs, Peripheral Blood Mononuclear Cells, business |
| الوصف: | Graphical abstract Several plants have traditionally been used since antiquity to treat various gastroenteritis and respiratory symptoms similar to COVID-19 outcomes. The common symptoms of COVID-19 include fever or chills, cold, cough, flu, headache, diarrhoea, tiredness/fatigue, sore throat, loss of taste or smell, asthma, shortness of breath, or difficulty breathing, etc. This study aims to find out the plants and plant-derived products which are being used by the COVID-19 infected patients in Bangladesh and how those plants are being used for the management of COVID-19 symptoms. In this study, online and partially in-person survey interviews were carried out among Bangladeshi respondents. We selected Bangladeshi COVID-19 patients who were detected Coronavirus positive (+) by RT-PCR nucleic acid test and later recovered. Furthermore, identified plant species from the surveys were thoroughly investigated for safety and efficacy based on the previous ethnomedicinal usage reports. Based on the published data, they were also reviewed for their significant potentialities as antiviral, anti-inflammatory, and immunomodulatory agents. We explored comprehensive information about a total of 26 plant species, belonging to 23 genera and 17 different botanical families, used in COVID-19 treatment as home remedies by the respondents. Most of the plants and plant-derived products were collected directly from the local marketplace. According to our survey results, greatly top 5 cited plant species measured as per the highest RFC value are Camellia sinensis (1.0) > Allium sativum (0.984) > Azadirachta indica (0.966) > Zingiber officinale (0.966) > Syzygium aromaticum (0.943). Previously published ethnomedicinal usage reports, antiviral, anti-inflammatory, and immunomodulatory activity of the concerned plant species also support our results. Thus, the survey and review analysis simultaneously reveals that these reported plants and plant-derived products might be promising candidates for the treatment of COVID-19. Moreover, this study clarifies the reported plants for their safety during COVID-19 management and thereby supporting them to include in any future pre-clinical and clinical investigation for developing herbal COVID-19 therapeutics. |
| تدمد: | 1319-562X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb3987308abcc1d8a8d204193a54c90 https://doi.org/10.1016/j.sjbs.2021.07.036 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....9cb3987308abcc1d8a8d204193a54c90 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1319562X |
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