Normative spectral domain optical coherence tomography data on macular and retinal nerve fiber layer thickness in Indians
| العنوان: | Normative spectral domain optical coherence tomography data on macular and retinal nerve fiber layer thickness in Indians |
|---|---|
| المؤلفون: | Bindu Appukuttan, Sobha Sivaprasad, Anantharaman Giridhar, Mahesh Gopalakrishnan |
| المصدر: | Indian Journal of Ophthalmology Indian Journal of Ophthalmology, Vol 62, Iss 3, Pp 316-321 (2014) |
| بيانات النشر: | Medknow Publications & Media Pvt Ltd, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Male, Aging, retinoschisis, visual impairment, retinal sensitivity, lcsh:Ophthalmology, Reference Values, Ethnicity, Macula Lutea, Prospective Studies, Homocysteine, orbit, fixation, vascular endothelial growth factor, ischemic optic neuropathy, sutureless manual small-incision cataract surgery, Central retinal vein occlusion, subconjunctival incision, normative, retinal vein occlusion, optic disc pit, Indian population, medicine.medical_specialty, Clinical profile, Spectral domain, thyroid exophthalmos, intravitrealbevacizumab, macular thickness, Age, Optical coherence tomography, Humans, myopia, Aged, macular edema, Capsular tension ring, retinal nerve fiber layer, medicine.disease, Decompression of the orbit, eye diseases, Normative database, Ophthalmology, Cross-Sectional Studies, chemistry, lcsh:RE1-994, phacoemulsification, Limbus incision, intravitrealtriamcinolone acetonide, intraocular pressure, Retinal Ganglion Cells, genetic structures, Nerve fiber layer, Optic disk, intraocular lens, Glaucoma, humphrey visual field, chemistry.chemical_compound, Nerve Fibers, Diabetic macular edema, gender, diplopia, medicine.diagnostic_test, total cholesterol, Indian, wound construction, microperimeter, Middle Aged, normative data, medicine.anatomical_structure, high density lipoprotein, cataract, Original Article, Female, optic neuritis treatment trial, Tomography, Optical Coherence, posterior capsular opacification, Adult, lipid profiles, Optic Disk, monocyte chemoattractant protein-1, Compressive optic neuropathy, body mass index, soluble intracellular adhesion molecule-1, retinal detachment, Young Adult, medicine, Contrast sensitivity, triglyceride, optic neuritis, thyroid ophthalmopathy, business.industry, Reproducibility of Results, Retinal, multifocal visual evoked potential, sense organs, business |
| الوصف: | Aim: To provide the normative data of macular and retinal nerve fiber layer (RNFL) thickness in Indians using spectral domain OCT (Spectralis OCT, Heidelberg Engineering, Germany) and to evaluate the effects of age, gender, and refraction on these parameters. Design: Observational, cross-sectional study. Materials and Methods: The eyes of 105 healthy patients aged between 20-75 years, with no ocular disease and best corrected visual acuity of 20/20, were scanned using standard scanning protocols by a single examiner. Exclusion criteria included glaucoma, retinal diseases, diabetes, history of prior intraocular surgery or laser treatment. The mean macular and RNFL thickness were recorded, and the effects of age, gender, and refraction on these parameters were evaluated. This data was compared with published literature on Caucasians to assess the ethnic variations of these parameters. Results: The normal central foveal thickness in healthy Indian eyes measured using Spectralis OCT was 260.1 ± 18.19 ΅m. The nasal inner quadrant showed maximum retinal thickness (338.88 ± 18.17 ΅m).The mean RNFL thickness was 101.43 ± 8.63 ΅m with maximum thickness in the inferior quadrant. The central foveal thickness showed a gender-based difference ( P = 0.005) but did not correlate significantly with age ( P = 0.134), whereas the parafoveal, perifoveal thickness, macular volume, and RNFL thickness showed significant negative correlation with age. Conclusions: Our study provides the normative database for Indians on Spectralis OCT. It also suggests that age should be considered while interpreting the macular thickness and RNFL, whereas gender should also be given consideration in central foveal thickness. |
| اللغة: | English |
| تدمد: | 1998-3689 0301-4738 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd0ddf95c0047639ba82bb4b0f77d7d http://europepmc.org/articles/PMC4061670 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....9cd0ddf95c0047639ba82bb4b0f77d7d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19983689 03014738 |
|---|