Synthesis, characterization, antibacterial and antifungal evaluation of novel cyclohexanone benzoylhydrazones
| العنوان: | Synthesis, characterization, antibacterial and antifungal evaluation of novel cyclohexanone benzoylhydrazones |
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| المؤلفون: | Gültaze Çapan, Emel Mataracı-Kara, Gökçe Cihan-Üstündağ |
| المصدر: | Volume: 49, Issue: 3 142-147 İstanbul Journal of Pharmacy |
| بيانات النشر: | İstanbul Üniversitesi, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Hydrazone,cyclohexanone,antibacterial activity,antifungal activity, biology, Farmakoloji ve Eczacılık, Electrospray ionization, Pharmaceutical Science, Cyclohexanone, Pharmacy, medicine.disease_cause, biology.organism_classification, Antimicrobial, Candida parapsilosis, Microanalysis, chemistry.chemical_compound, chemistry, Staphylococcus aureus, Staphylococcus epidermidis, medicine, Pharmacology and Pharmacy, Bacteria, Nuclear chemistry |
| الوصف: | A novel series of benzoyl hydrazones (2a-j) were synthesized and evaluated, in vitro, for antimicrobial activity against selected bacteria and fungi. The structures of the compounds were established by IR, 1 H-NMR, 13C-NMR (APT), electrospray ionization mass spectrometry (ESI-MS) and microanalysis (C, H, N). All of the tested compounds, except for compound 2h, displayed weak antibacterial properties against Staphylococcus epidermidis ATCC 12228 and Staphylococcus aureus ATCC 29213. Compounds 2a, 2b, 2e, 2f and 2i further exhibited marginal antifungal activity against Candida parapsilosis. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2587-2087 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce12b37e90b7a5ff7b36fa296f695fa https://dergipark.org.tr/tr/pub/iujp/issue/51768/628756 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....9ce12b37e90b7a5ff7b36fa296f695fa |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 25872087 |
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