New standards have been recently defined and implemented enabling a reliable exchange of pharmacometric models across software tools, and facilitating collaborative drug and disease modeling and simulation (M&S) activities. Among these, the Standard Output (SO) has been proposed as the tool‐independent exchange and storage format for typical M&S results. The SO integration within the Drug Disease Model Resource (DDMoRe) interoperability framework (IOF) has already shown its potential for enabling effective data flow across modeling tasks and facilitating information retrieval.