Five-Year Outcomes of Successful Percutaneous Coronary Intervention with Drug-Eluting Stents versus Medical Therapy for Chronic Total Occlusions
| العنوان: | Five-Year Outcomes of Successful Percutaneous Coronary Intervention with Drug-Eluting Stents versus Medical Therapy for Chronic Total Occlusions |
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| المؤلفون: | Byoung Geol Choi, Woohyeun Kim, Hong Euy Lim, Ahmed Mashaly, Won Young Jang, Eun Jin Park, Seung-Woon Rha, Chang Gyu Park, Eung Ju Kim, Man Jong Baek, Se Yeon Choi, Hong Seog Seo, Cheol Ung Choi, Hu Li, Jae Kyeong Byun, Jin Oh Na, Yang Gi Ryu, Jah Yeon Choi, Yoonjee Park, Dong Joo Oh |
| المصدر: | Yonsei Medical Journal |
| بيانات النشر: | Yonsei University College of Medicine, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Cardiac & Cardiovascular Systems, medicine.medical_treatment, Myocardial Infarction, 030204 cardiovascular system & hematology, Revascularization, Coronary Angiography, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, drug-eluting stent, Medicine, Humans, 030212 general & internal medicine, Myocardial infarction, Propensity Score, Stroke, Aged, Proportional Hazards Models, business.industry, Incidence, Hazard ratio, percutaneous coronary intervention, Percutaneous coronary intervention, Drug-Eluting Stents, General Medicine, Middle Aged, medicine.disease, medical therapy, Chronic total occlusion, Logistic Models, Treatment Outcome, Coronary Occlusion, Drug-eluting stent, Coronary occlusion, Conventional PCI, Cardiology, Original Article, Female, business |
| الوصف: | Purpose Many recent studies have reported that successful percutaneous coronary intervention (PCI) with drug-eluting stents (DESs) for chronic total occlusion (CTO) has more beneficial effects than failed CTO-PCI; however, there are only limited data available from comparisons of successful CTO-PCI with medical therapy (MT) in the Korean population. Materials and methods A total of 840 consecutive CTO patients who underwent diagnostic coronary angiography, receiving either PCI with DESs or MT, were enrolled. Patients were divided into two groups according to the treatment assigned. To adjust for potential confounders, propensity score matching (PSM) analysis was performed using logistic regression. Individual major clinical outcomes and major adverse cardiac events, a composite of total death, myocardial infarction (MI), stroke, and revascularization, were compared between the two groups up to 5 years. Results After PSM, two propensity-matched groups (265 pairs, n=530) were generated, and the baseline characteristics were balanced. Although the PCI group showed a higher incidence of target lesion and vessel revascularization on CTO, the incidence of MI tended to be lower [hazard ratio (HR): 0.339, 95% confidence interval (CI): 0.110 to 1.043, p=0.059] and the composite of total death or MI was lower (HR: 0.454, 95% CI: 0.224 to 0.919, p=0.028), compared with the MT group up to 5 years. Conclusion In this study, successful CTO PCI with DESs was associated with a higher risk of repeat PCI for the target vessel, but showed a reduced incidence of death or MI. |
| اللغة: | English |
| تدمد: | 1976-2437 0513-5796 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2ac0468977bbf61637bf1966504078 http://europepmc.org/articles/PMC5990674 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....9d2ac0468977bbf61637bf1966504078 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19762437 05135796 |
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