Supplementary Figure 2 from CCT244747 Is a Novel Potent and Selective CHK1 Inhibitor with Oral Efficacy Alone and in Combination with Genotoxic Anticancer Drugs

التفاصيل البيبلوغرافية
العنوان: Supplementary Figure 2 from CCT244747 Is a Novel Potent and Selective CHK1 Inhibitor with Oral Efficacy Alone and in Combination with Genotoxic Anticancer Drugs
المؤلفون: Michelle D. Garrett, Ian Collins, Suzanne A. Eccles, Florence I. Raynaud, Louis Chesler, John C. Reader, G. Wynne Aherne, Simon P. Robinson, Yann Jamin, Thomas P. Matthews, Michael Lainchbury, Kathy J. Boxall, Elizabeth L. Smith, Albert Hallsworth, Gary Box, Alexis K. De Haven Brandon, Melanie R. Valenti, Angela Hayes, Paul D. Eve, Mike I. Walton
بيانات النشر: American Association for Cancer Research (AACR), 2023.
سنة النشر: 2023
الوصف: PDF file, 92K, Supplementary Figure 2. A constrained, scaffold docking model of CCT244747 in the ATP pocket of human CHK1 realized using the SAR-020106 X-ray crystal structure (PDB 2ym8).
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db6fcbdeb80531e3ddd7d42e0cafbdd
https://doi.org/10.1158/1078-0432.22445639
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....9db6fcbdeb80531e3ddd7d42e0cafbdd
قاعدة البيانات: OpenAIRE