Neural Function Before and After Mindfulness-Based Cognitive Therapy in Anxious Adolescents at Risk for Developing Bipolar Disorder
| العنوان: | Neural Function Before and After Mindfulness-Based Cognitive Therapy in Anxious Adolescents at Risk for Developing Bipolar Disorder |
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| المؤلفون: | Christina M. Luberto, Lauren Stahl, Jeffrey R. Strawn, Wade Weber, Sian Cotton, Richard W. Sears, James C. Eliassen, Melissa P. DelBello, L. Rodrigo Patino |
| المصدر: | Journal of Child and Adolescent Psychopharmacology. 26:372-379 |
| بيانات النشر: | Mary Ann Liebert Inc, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Bipolar Disorder, Mindfulness, Adolescent, medicine.medical_treatment, Neuropsychological Tests, Audiology, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, medicine, Humans, Pharmacology (medical), Longitudinal Studies, Bipolar disorder, Child, Psychiatry, Mindfulness-based cognitive therapy, Cognitive Behavioral Therapy, medicine.diagnostic_test, Separation anxiety disorder, Brain, Original Articles, medicine.disease, Anxiety Disorders, Magnetic Resonance Imaging, 030227 psychiatry, Psychiatry and Mental health, Treatment Outcome, Pediatrics, Perinatology and Child Health, Cognitive therapy, Anxiety, Female, medicine.symptom, Functional magnetic resonance imaging, Psychology, Insula, 030217 neurology & neurosurgery |
| الوصف: | We sought to evaluate the neurophysiology of mindfulness-based cognitive therapy for children (MBCT-C) in youth with generalized, social, and/or separation anxiety disorder who were at risk for developing bipolar disorder.Nine youth (mean age: 13 ± 2 years) with a generalized, social, and/or separation anxiety disorder and a parent with bipolar disorder completed functional magnetic resonance imaging (fMRI) while performing a continuous processing task with emotional and neutral distractors (CPT-END) prior to and following 12 weeks of MBCT-C.MBCT-C was associated with increases in activation of the bilateral insula, lentiform nucleus, and thalamus, as well as the left anterior cingulate while viewing emotional stimuli during the CPT-END, and decreases in anxiety were correlated with change in activation in the bilateral insula and anterior cingulate during the viewing of emotional stimuli (p 0.05, uncorrected; p 0.005 corrected; cluster size, 37 voxels).MBCT-C treatment in anxious youth with a familial history of bipolar disorder is associated with increased activation of brain structures that subserve interoception and the processing of internal stimuli-functions that are ostensibly improved by this treatment. |
| تدمد: | 1557-8992 1044-5463 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dc39fd544349f33c7dea10d3ad4b661 https://doi.org/10.1089/cap.2015.0054 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....9dc39fd544349f33c7dea10d3ad4b661 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15578992 10445463 |
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