Application of non-contrasted computed tomography and diffusion-weighted imaging protocols for endovascular treatment selection in patients with late-presenting or wake-up strokes
| العنوان: | Application of non-contrasted computed tomography and diffusion-weighted imaging protocols for endovascular treatment selection in patients with late-presenting or wake-up strokes |
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| المؤلفون: | Ren Hecheng, Wang Shuyuan, Yin Long, Wei Ming, Ma Lin |
| المصدر: | Arquivos de Neuro-Psiquiatria v.79 n.11 2021 Arquivos de neuro-psiquiatria Academia Brasileira de Neurologia instacron:ABNEURO Arquivos de Neuro-Psiquiatria, Vol 79, Iss 11, Pp 943-949 (2021) |
| بيانات النشر: | Academia Brasileira de Neurologia - ABNEURO, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Computed tomography, Neurosciences. Biological psychiatry. Neuropsychiatry, Endovascular Treatment, Brain Ischemia, Non-contrast Computed Tomography, Occlusion, medicine, Humans, In patient, cardiovascular diseases, Endovascular treatment, Stroke, Ischemic Stroke, Thrombectomy, medicine.diagnostic_test, business.industry, Endovascular Procedures, Magnetic resonance imaging, medicine.disease, Treatment Outcome, Diffusion Magnetic Resonance Imaging, Neurology, Infarct volume, Neurology (clinical), Radiology, business, Diffusion MRI, RC321-571 |
| الوصف: | Background: Among patients with acute ischemic stroke with a mismatch between deficit severity and infarct volume, thrombectomy performed within a 6-24 hours time window has efficacy and safety similar to treatment within 6 hours. However, whether magnetic resonance imaging with T2 diffusion-weighted imaging (DWI) is feasible remains to be validated. Objective: To investigate prognosis among stroke patients receiving endovascular treatment (EVT) within 6 hours and 6-24 hours using non-contrasted computed tomography (NCCT) and DWI. Methods: Overall, 209 anterior-circulation ischemic stroke patients with large-vessel occlusion who underwent EVT were divided into ≤ 6 hours and 6-24 hours groups. Patients presenting symptoms within 6 hours were treated if their NIHSS score was ≥ 7 and ASPECTS score was ≥ 5, whereas those with wake-up stroke (WUS) or presenting symptoms 6-24 hours after last seen well (WUS/late-presenting stroke, LPS) were managed if their NIHSS score was ≥ 7 and ASPECTS score was ≥ 5. Results: The percentages of patients undergoing intracranial stenting and intracranial ballooning without stenting significantly differed between two groups (p < 0.001). Grades 0, 1, 2a and 2b recanalization rates did not differ between the 6 hours and 6-24 hours groups (all p > 0.05). Grade 3 recanalization rate in the 6 hours group was significantly lower than in the 6-24 hours group (p = 0.043). The 3-month Rankin Scale score did not significantly differ between the two groups (p = 0.629). Conclusions: EVT is a safe and effective treatment for patients with WUS and LPS selected through NCCT and DWI-based simple imaging. |
| وصف الملف: | text/html |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f368eecfe29bc2f42c28aa2baf9fa6b http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021001100943 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....9f368eecfe29bc2f42c28aa2baf9fa6b |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |