ESBL-Producing Escherichia coli Carrying CTX-M Genes Circulating among Livestock, Dogs, and Wild Mammals in Small-Scale Farms of Central Chile
| العنوان: | ESBL-Producing Escherichia coli Carrying CTX-M Genes Circulating among Livestock, Dogs, and Wild Mammals in Small-Scale Farms of Central Chile |
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| المؤلفون: | Andrés Opazo-Capurro, Javier Millán, Jose M. Munita, Julio A. Benavides, Macarena Otto Medina, Marília Salgado-Caxito, Lina M Rivas, P Muñoz, Ana Piñeiro |
| المصدر: | Antibiotics Volume 10 Issue 5 Antibiotics, Vol 10, Iss 510, p 510 (2021) |
| بيانات النشر: | Multidisciplinary Digital Publishing Institute, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | 0301 basic medicine, Microbiology (medical), Veterinary medicine, wildlife, 030106 microbiology, Wildlife, RM1-950, extended-spectrum beta-lactamases, medicine.disease_cause, Disease cluster, blaCTX-M, E. coli, Biochemistry, Microbiology, 03 medical and health sciences, Antibiotic resistance, domestic animals, Genotype, medicine, biology.domesticated_animal, Pharmacology (medical), antimicrobial resistance, General Pharmacology, Toxicology and Pharmaceutics, Chile, Escherichia coli, biology, business.industry, Host (biology), 030104 developmental biology, Infectious Diseases, Livestock, Therapeutics. Pharmacology, European rabbit, business |
| الوصف: | Antibiotic-resistant bacteria of critical importance for global health such as extended-spectrum beta-lactamases-producing (ESBL)-Escherichia coli have been detected in livestock, dogs, and wildlife worldwide. However, the dynamics of ESBL-E. coli between these animals remains poorly understood, particularly in small-scale farms of low and middle-income countries where contact between species can be frequent. We compared the prevalence of fecal carriage of ESBL-E. coli among 332 livestock (207 cows, 15 pigs, 60 horses, 40 sheep, 6 goats, 4 chickens), 82 dogs, and wildlife including 131 European rabbits, 30 rodents, and 12 Andean foxes sharing territory in peri-urban localities of central Chile. The prevalence was lower in livestock (3.0%) and wildlife (0.5%) compared to dogs (24%). Among 47 ESBL-E. coli isolates recovered, CTX-M-group 1 was the main ESBL genotype identified, followed by CTX-M-groups 2, 9, 8, and 25. ERIC-PCR showed no cluster of E. coli clones by either host species nor locality. To our knowledge, this is the first report of ESBL-E. coli among sheep, cattle, dogs, and rodents of Chile, confirming their fecal carriage among domestic and wild animals in small-scale farms. The high prevalence of ESBL-E. coli in dogs encourages further investigation on their role as potential reservoirs of this bacteria in agricultural settings. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2079-6382 |
| DOI: | 10.3390/antibiotics10050510 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f75fcbb309b49a94a1a04b49f15d3d6 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....9f75fcbb309b49a94a1a04b49f15d3d6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20796382 |
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| DOI: | 10.3390/antibiotics10050510 |