The Safety and Feasibility of Laparoscopic Surgery for Very Low Rectal Cancer: A Retrospective Analysis Based on a Single Center’s Experience
| العنوان: | The Safety and Feasibility of Laparoscopic Surgery for Very Low Rectal Cancer: A Retrospective Analysis Based on a Single Center’s Experience |
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| المؤلفون: | Bong-Hyeon Kye, Jun-Gi Kim, Hyung-Jin Kim, Hyeon-Min Cho, Hyuk-Jun Chung |
| المصدر: | Biomedicines Volume 9 Issue 11 Biomedicines, Vol 9, Iss 1720, p 1720 (2021) |
| بيانات النشر: | Multidisciplinary Digital Publishing Institute, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Laparoscopic surgery, medicine.medical_specialty, oncologic outcomes, QH301-705.5, business.industry, Abdominoperineal resection, medicine.medical_treatment, Mortality rate, Medicine (miscellaneous), Single Center, sphincter saving surgery, laparoscopic surgery, Article, General Biochemistry, Genetics and Molecular Biology, Surgery, Low rectal cancer, Retrospective analysis, Rectal cancer surgery, Medicine, Biology (General), very low rectal cancer, business, Coloanal anastomosis |
| الوصف: | In this work we intend to validate the long-term oncologic outcomes for very low rectal cancer over the past 20 years and to determine whether laparoscopic procedures are useful options for very low rectal cancer. A total of 327 patients, who electively underwent laparoscopic rectal cancer surgery for a lesion within 5 cm from the anal verge, were enrolled in this study and their long-term outcomes were reviewed retrospectively. Of 327 patients, 70 patients underwent laparoscopic low anterior resection (LAR), 164 underwent laparoscopic abdominal transanal proctosigmoidocolectomy with coloanal anastomosis (LATA), and 93 underwent laparoscopic abdominoperineal resection (APR). The conversion rate was 1.22% (4/327). The overall postoperative morbidity rate was 26.30% (86/327). The 5-year disease free survival (DFS), 5-year overall survival (OS), and 3-year local recurrence (LR) were 64.3%, 79.7%, and 9.2%, respectively. The CRM involvement was a significant independent factor for DFS (p = 0.018) and OS (p = 0.042) in multivariate analysis. Laparoscopic APR showed poorer 5-year DFS (47.8%), 5-year OS (64.0%), and 3-year LR (17.6%) than laparoscopic LAR (74.1%, 86.4%, 1.9%) and laparoscopic LATA (69.2%, 83.6%, 9.2%). Laparoscopic procedures for very low rectal cancer including LAR, LATA, and APR could be good surgical options in selective patients with very low rectal cancer. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2227-9059 |
| DOI: | 10.3390/biomedicines9111720 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0552247a330ee2c92de37da90f6b532 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....a0552247a330ee2c92de37da90f6b532 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22279059 |
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| DOI: | 10.3390/biomedicines9111720 |