Gulls as Sources of Environmental Contamination by Colistin-resistant Bacteria
| العنوان: | Gulls as Sources of Environmental Contamination by Colistin-resistant Bacteria |
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| المؤلفون: | Christina Ahlstrom, Kevin T. Bentler, Jeffrey C. Chandler, Nicole L. Barrett, Alan B. Franklin, Andrew M. Ramey, Loredana M. McCurdy, Susan A. Shriner, Jonas Bonnedahl |
| المصدر: | Scientific Reports Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020) |
| بيانات النشر: | Nature Publishing Group UK, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 0301 basic medicine, Livestock, medicine.drug_class, 030106 microbiology, Antibiotics, Zoology, lcsh:Medicine, medicine.disease_cause, Antimicrobial resistance, Article, Microbiology in the medical area, 03 medical and health sciences, Charadriiformes, Feces, Drug Resistance, Bacterial, medicine, Mikrobiologi inom det medicinska området, Escherichia coli, Animals, Humans, lcsh:Science, Ecological epidemiology, Bacterial Shedding, Multidisciplinary, biology, business.industry, Escherichia coli Proteins, lcsh:R, biology.organism_classification, Fecal coliform, 030104 developmental biology, embryonic structures, Colistin, lcsh:Q, Flock, Bacterial infection, business, Bacteria, hormones, hormone substitutes, and hormone antagonists, medicine.drug, Environmental Monitoring |
| الوصف: | In 2015, the mcr-1 gene was discovered in Escherichia coli in domestic swine in China that conferred resistance to colistin, an antibiotic of last resort used in treating multi-drug resistant bacterial infections in humans. Since then, mcr-1 was found in other human and animal populations, including wild gulls. Because gulls could disseminate the mcr-1 gene, we conducted an experiment to assess whether gulls are readily colonized with mcr-1 positive E. coli, their shedding patterns, transmission among conspecifics, and environmental deposition. Shedding of mcr-1 E. coli by small gull flocks followed a lognormal curve and gulls shed one strain >10(1) log10 CFU/g in their feces for 16.4 days, which persisted in the environment for 29.3 days. Because gulls are mobile and can shed antimicrobial-resistant bacteria for extended periods, gulls may facilitate transmission of mcr-1 positive E. coli to humans and livestock through fecal contamination of water, public areas and agricultural operations. Funding Agencies|U.S. Department of Agriculture, Animal and Plant Health Inspection ServiceUnited States Department of Agriculture (USDA); U.S. Geological Survey through the Contaminants Biology Program of the Environmental Health Mission Area; U.S. Geological Survey through Wildlife Program of the Ecosystems Mission Area |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2045-2322 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0766111444babbdb29fa5d2be9d6025 http://europepmc.org/articles/PMC7064522 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....a0766111444babbdb29fa5d2be9d6025 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20452322 |
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