Assesement of serum Sfrp5/Wnt-5a level and its utility in the risk stratification of treatment naïve patients with metabolic syndrome
| العنوان: | Assesement of serum Sfrp5/Wnt-5a level and its utility in the risk stratification of treatment naïve patients with metabolic syndrome |
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| المؤلفون: | Suraj Singh Yadav, Sartaj Hussain, Pradeep Dwivedi, Sanjay Khattri, Kamal Kumar Sawlani, Kauser Usman |
| المصدر: | Journal of Immunoassay and Immunochemistry. 44:1-12 |
| بيانات النشر: | Informa UK Limited, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Medical Laboratory Technology, Clinical Biochemistry, Immunology, Immunology and Allergy |
| الوصف: | Our study focused on investigating the clinical significance of serum Sfrp5/Wnt-5a levels as a risk marker in metabolic syndrome (MetS). The study involved a total of 107 treatment-naive MetS cases and 100 controls with similar age and sex belonging to northern India. The profiling of clinical, biochemical, and anthropometric variables was done. ELISA methods were employed for serum cytokine estimation. Serum Sfrp5 was inversely correlated with BMI, WC, SBP, DBP, FPG, TG, fasting insulin level, and HOMA-IR in both males and females. The best cutoff value for Sfrp5 to predict MetS in males was ≤40.48 ng/ml (sensitivity 53.70% and specificity 90.48%), while in female, it was ≤66.67 ng/ml (sensitivity 98.11% and specificity 34.48%). MetS occurrence decreased with increasing concentration of Sfrp5 with an odds ratio (OR) of 0.95 (95% CI = 0.92-0.98 |
| تدمد: | 1532-4230 1532-1819 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1646934ac0ccbf3ed85dd2f8b88e1c5 https://doi.org/10.1080/15321819.2022.2104125 |
| رقم الأكسشن: | edsair.doi.dedup.....a1646934ac0ccbf3ed85dd2f8b88e1c5 |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 15324230 15321819 |
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