Consensus statement on safety measures for pressurized intraperitoneal aerosol chemotherapy
| العنوان: | Consensus statement on safety measures for pressurized intraperitoneal aerosol chemotherapy |
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| المؤلفون: | Daniel Clerc, Arnaud Girardot-Miglierina, Olivia Sgarbura, Martin Hübner, Mohammad Alyami, Laurent Villeneuve, Marc-André Reymond |
| المساهمون: | ISSPP PIPAC study group |
| المصدر: | Pleura and Peritoneum, Vol 6, Iss 4, Pp 139-149 (2021) Pleura and peritoneum, vol. 6, no. 4, pp. 139-149 Pleura and Peritoneum |
| بيانات النشر: | Walter de Gruyter GmbH, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | safety, medicine.medical_specialty, Chemotherapy, expert consensus, Statement (logic), business.industry, medicine.medical_treatment, Specialties of internal medicine, Aerosol, RC581-951, personal protective equipment, Internal Medicine, PIPAC, education and training, medicine, Medicine, pipac, Intensive care medicine, business, Research Article |
| الوصف: | Objectives Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a promising treatment for peritoneal cancer that entails, however, potential risks for the caregivers in the operating room (OR). This study aimed to reach a consensus within the PIPAC community on a comprehensive safety protocol. Methods Active PIPAC centers were invited to participate in a two-round Delphi process on 43 predefined items: concise summaries of the existing evidence were presented together with questions formulated using the population, intervention, comparator, and outcome framework. According to the Grading of Recommendations Assessment, Development, and Evaluation, the strength of recommendation was voted by panelists, accepting a consensus threshold of ≥50% of the agreement for any of the four grading options, or ≥70% in either direction. Results Forty-seven out of 66 invited panelists answered both rounds (response rate 76%). The consensus was reached for 41 out of 43 items (95.3%). Strong and weak recommendations were issued for 30 and 10 items, respectively. A positive consensual recommendation was issued to activate laminar airflow without specific strength, neither strong nor weak. No consensus was reached for systematic glove change for caregivers with a high risk of exposure and filtering facepiece mask class 3 for caregivers with low risk of exposure. Conclusions A high degree of consensus was reached for a comprehensive safety protocol for PIPAC, adapted to the risk of exposure for the different caregivers in the OR. This consensus can serve as a basis for education and help reach a high degree of adherence in daily practice. |
| وصف الملف: | application/pdf |
| تدمد: | 2364-768X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3fd6157913da0ac0358f85b5e574ba1 https://doi.org/10.1515/pp-2021-0125 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....a3fd6157913da0ac0358f85b5e574ba1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 2364768X |
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