Injectable platelet‐rich fibrin for perioral rejuvenation as assessed by 3D lip volume imaging
| العنوان: | Injectable platelet‐rich fibrin for perioral rejuvenation as assessed by 3D lip volume imaging |
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| المؤلفون: | Rudolf Seemann, Omar Hamid, Haidar Hassan, Daniel J. Quinlan |
| المصدر: | Journal of Cosmetic Dermatology. 20:3270-3277 |
| بيانات النشر: | Wiley, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Lip augmentation, biology, business.industry, Facial rejuvenation, Dentistry, Cosmetic Techniques, Dermatology, Lip, Platelet-rich fibrin, Fibrin, Skin Aging, stomatognathic diseases, Platelet-Rich Fibrin, biology.protein, Humans, Rejuvenation, Medicine, Female, Prospective Studies, Autologous platelet, Intradermal injection, business, Adverse effect |
| الوصف: | BACKGROUND Various injectable autologous platelet aggregate preparations have been developed and used for facial rejuvenation. Limited evidence exists for the use of these for augmentation of the lip. OBJECTIVES This prospective, uncontrolled, single-center study evaluated the qualitative and quantitative effects of an injectable platelet-rich fibrin preparation (known as i-PRF+) for lip augmentation. PATIENTS/METHODS PRF® PROCESS system technology was used to prepare i-PRF+ supernatant. Ten healthy females were included in the study and received a single intradermal injection of i-PRF+ in the upper and lower lips (5 ml in each quadrant, total ~2 ml). Participants were followed for 3 months post-procedure. The efficacy of the procedure was assessed qualitatively by a subjective patient-reported outcome (FACE-Q) assessment and quantitatively by objective 3D skin surface volume analysis (ProFace® ) at baseline and after 3 months. RESULTS FACE-Q scales that measure satisfaction with skin and lip showed a statistically significant improvement from baseline (p = 0.04 and p = 0.02, respectively). Satisfaction with lip lines showed a numerical improvement with mean total scores for adverse effect scales related to the skin and lips reduced at 2 weeks post-procedure (p = 0.03 and p = 0.13, respectively). Overall lip volume at 3-month follow-up was unchanged (p = 0.11). The treatment was well tolerated with only minor adverse effects. CONCLUSIONS A single session of i-PRF+ injections resulted in significant lip rejuvenation at 3-month follow-up, shown by improved patient-reported outcome measure. No significant change in lip volume was observed. |
| تدمد: | 1473-2165 1473-2130 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53787d720a59cee8181abb69c8932a2 https://doi.org/10.1111/jocd.14394 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....a53787d720a59cee8181abb69c8932a2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14732165 14732130 |
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