Analysis of Organoarsenic Compounds Concentration in Fish with the Newly Developed LC-MS/MS Method
| العنوان: | Analysis of Organoarsenic Compounds Concentration in Fish with the Newly Developed LC-MS/MS Method |
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| المؤلفون: | Keiko Nakamuta, Yohei Kataoka, Koichi Akaki, Etsuko Miyazaki, Hironori Towatari, Takahiro Watanabe |
| المصدر: | Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi). 61:86-94 |
| بيانات النشر: | Japanese Society for Food Hygiene and Safety, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Organoarsenic compounds, Chromatography, biology, Fishes, chemistry.chemical_element, General Medicine, Monomethylarsonic acid, biology.organism_classification, Arsenicals, Arsenic, chemistry.chemical_compound, Filefish, Seafood, chemistry, Tandem Mass Spectrometry, Lc ms ms, Toxicity, Animals, Fish |
| الوصف: | Most fish contain some kinds of organoarsenic compounds. To assess the health risk for the chronic effects due to intake of these compounds, it is necessary to quantify the concentration of each chemical form, since the toxicity is difference depending on the form. We developed and validated the LC-MS/MS method to determine the concentration of monomethylarsonic acid (MMA), dimethylarsinic acid (DMA), trimethylarsine oxide (TMAO), tetramethylarsonium (TeMA), arsenobetaine (AB), and arsenocholine (AC) in fish. Using this method, we quantified the concentration of each organoarsenic compounds and total arsenic in 50 fish samples from across 10 groups. Total arsenic concentration ranged from 0.53 to 25 mg/kg in all samples, except for in thread-sail filefish where the concentration ranged from 8.3 to 25 mg/kg. With the exception of sardines, in all samples AB was found at the highest level in relation to the total arsenic concentration. In sardines, the concentration of DMA was higher than that of AB, accounting for 16 to 24% of total arsenic. In red sea bream, concentrations of total arsenic, AB, and AC in farm-raised fish were lower than those in wild-caught fish. |
| تدمد: | 1882-1006 0015-6426 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a600127735ba2b0c2101c45c5fbae77a https://doi.org/10.3358/shokueishi.61.86 |
| رقم الأكسشن: | edsair.doi.dedup.....a600127735ba2b0c2101c45c5fbae77a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18821006 00156426 |
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