Papular xanthomas and erosive arthritis in a 3 year old girl, is this a new MRH variant?
| العنوان: | Papular xanthomas and erosive arthritis in a 3 year old girl, is this a new MRH variant? |
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| المؤلفون: | Brandt Groh, Andrea L. Zaenglein, Polly J. Ferguson, Catherine A. Bingham, Catalina Matiz |
| المصدر: | Pediatric Rheumatology Online Journal, Vol 7, Iss 1, p 15 (2009) Pediatric Rheumatology Online Journal |
| بيانات النشر: | BMC, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | Pathology, medicine.medical_specialty, Papular xanthoma, lcsh:Diseases of the musculoskeletal system, Arthritis, Case Report, Etanercept, Rheumatology, Prednisone, Internal medicine, medicine, Immunology and Allergy, Pediatrics, Perinatology, and Child Health, business.industry, lcsh:RJ1-570, Multicentric reticulohistiocytosis, lcsh:Pediatrics, medicine.disease, Dermatology, Infliximab, Pediatrics, Perinatology and Child Health, Methotrexate, lcsh:RC925-935, business, medicine.drug |
| الوصف: | Xanthomatous skin lesions and arthritis in children are not a common association. We present the case of a 3 year old girl who presented with xanthomatous lesions in the periungual region of both hands, around the nares and on her forehead, associated with significant arthritis that was clinically compatible with multicentric reticulohistiocytosis. However, pathology of the xanthomatous lesions was more suggestive of papular xanthoma, a disease that is not associated with arthritis. Based on her presentation and the negative lipid workup, she was treated for presumed multicentric reticulohistiocytosis. Multiple treatment strategies were utilized, with improvement on a combination of infliximab, methotrexate, and prednisone. We review the different diagnoses that should be considered in children with xanthomas and arthritis as well as the different pharmacologic therapies used in children with multicentric reticulohistiocytosis. |
| اللغة: | English |
| تدمد: | 1546-0096 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65ad54856e4bf1133158223c59ff9e2 http://www.ped-rheum.com/content/7/1/15 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....a65ad54856e4bf1133158223c59ff9e2 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 15460096 |
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