التفاصيل البيبلوغرافية
العنوان:
Comment on 'A common genetic variant is associated with adult and childhood obesity'
المؤلفون:
Jean Tichet , David Meyre , Michel Marre , Beverley Balkau , Marie-Aline Charles , Béatrice Jouret , Philippe Froguel , Christian Dina , Chantal Samson
المصدر:
Science (New York, N.Y.) . 315(5809)
سنة النشر:
2007
مصطلحات موضوعية:
Adult , Male , Population , 030209 endocrinology & metabolism , Biology , Polymorphism, Single Nucleotide , Childhood obesity , White People , Body Mass Index , 03 medical and health sciences , 0302 clinical medicine , Gene Frequency , Polymorphism (computer science) , Genetic variation , medicine , Humans , Family , Genetic Predisposition to Disease , Obesity , education , Child , Allele frequency , Genetics , education.field_of_study , Multidisciplinary , INSIG2 , Case-control study , Intracellular Signaling Peptides and Proteins , Genetic Variation , Membrane Proteins , medicine.disease , Case-Control Studies , Female , France
الوصف:
Herbert et al . (Reports, 14 April 2006, p. 279) reported an association between the INSIG2 gene variant rs7566605 and obesity in four sample populations, under a recessive model. We attempted to replicate this result in 10,265 Caucasian individuals, combining family-based, case-control, and general population studies, but found no support for a major role of this variant in obesity.
تدمد:
1095-9203
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a05ec1e972fc62b18a727f599e98cb https://pubmed.ncbi.nlm.nih.gov/16614226
رقم الأكسشن:
edsair.doi.dedup.....a6a05ec1e972fc62b18a727f599e98cb
قاعدة البيانات:
OpenAIRE
