The positive effects of surgery on symptomatic stereotactic radiation-induced peritumoral brain edema: A report of three cases
| العنوان: | The positive effects of surgery on symptomatic stereotactic radiation-induced peritumoral brain edema: A report of three cases |
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| المؤلفون: | Pietro Fiaschi, Roberto Stefini, Andrea Cividini, Giovanni Marco Sicuri, Stefano Peron, Alessandro Lacamera |
| المصدر: | Surgical Neurology International |
| بيانات النشر: | Scientific Scholar, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Side effect, medicine.medical_treatment, Case Report, Radiosurgery, Lesion, Meningioma, Brain swelling, Peritumoral brain edema, Vestibular schwannoma, 03 medical and health sciences, 0302 clinical medicine, Edema, medicine, Peritumoral Brain Edema, medicine.diagnostic_test, business.industry, Magnetic resonance imaging, medicine.disease, Surgery, 030220 oncology & carcinogenesis, Neurology (clinical), medicine.symptom, business, 030217 neurology & neurosurgery |
| الوصف: | Background: Peritumoral brain edema is an uncommon but life-threatening side effect of brain tumors radiosurgery. Medical therapy usually alleviates symptoms until edema spontaneously disappears. However, when peritumoral brain edema endangers the patient’s life or medical therapy fails to guarantee an acceptable quality of life, surgery might be considered. Case Description: Our report focuses on three patients who developed extensive peritumoral brain edema after radiosurgery. Two were affected by vestibular schwannomas and one by a skull-base meningioma. Peritumoral brain edema worsened despite maximal medical therapy in all cases; therefore, surgical removal of the radiated lesion was carried out. In the first patient, surgery was overdue and resulted in a fatal outcome. On the other hand, in the latter two cases surgery was quickly effective. In all three cases, an unmanageable brain swelling was not found at surgery. Conclusion: Surgical removal of brain tumors previously treated with radiosurgery was safe and effective in resolving shortly peritumoral brain edema. This solution should be considered in patients who do not respond to medical therapy and before worsening of clinical conditions. Interestingly, the expected brain swelling was not confirmed intraoperatively. In our experience, this magnetic resonance finding should not be considered a criterion to delay surgery. |
| اللغة: | English |
| تدمد: | 2152-7806 2229-5097 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f20d60ab99d8217b9e8fcaf37b98ab http://europepmc.org/articles/PMC8326067 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....a6f20d60ab99d8217b9e8fcaf37b98ab |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 21527806 22295097 |
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