The Chlorella variabilis NC64A Genome Reveals Adaptation to Photosymbiosis, Coevolution with Viruses, and Cryptic Sex
| العنوان: | The Chlorella variabilis NC64A Genome Reveals Adaptation to Photosymbiosis, Coevolution with Viruses, and Cryptic Sex |
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| المؤلفون: | David D. Dunigan, Susan Lucas, James R. Gurnon, Guillaume Blanc, Jasmyn Pangilinan, Garry A. Duncan, Igor V. Grigoriev, Astrid Terry, James L. Van Etten, Takashi Yamada, Mark Borodovsky, Juergen E. W. Polle, Alan Kuo, Asaf Salamov, Jean-Michel Claverie, Erika Lindquist, Irina Agarkova |
| المصدر: | Blanc, Guillaume; Duncan, Garry A.; Agarakova, Irina; Borodovsky, Mark; Gurnon, James; Kuo, Alan; et al.(2010). The Chlorella variabilis NC64A Genome Reveals Adaptation to Photosymbiosis, Coevolution with Viruses, and Cryptic Sex. The Plant Cell. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/24n461hm |
| بيانات النشر: | Oxford University Press (OUP), 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | food.ingredient, Nuclear gene, DNA, Plant, Molecular Sequence Data, Chlorella, Plant Science, Genome, In Brief, Evolution, Molecular, food, Plant Growth Regulators, Cell Wall, Chlorovirus, Botany, Symbiosis, Gene, Repetitive Sequences, Nucleic Acid, Expressed Sequence Tags, Genetics, Base Composition, biology, Reproduction, Trebouxiophyceae, Sequence Analysis, DNA, Cell Biology, biology.organism_classification, Paramecium bursaria, Flagella, Multigene Family, Horizontal gene transfer, Genome, Plant |
| الوصف: | Chlorella variabilis NC64A, a unicellular photosynthetic green alga (Trebouxiophyceae), is an intracellular photobiont of Paramecium bursaria and a model system for studying virus/algal interactions. We sequenced its 46-Mb nuclear genome, revealing an expansion of protein families that could have participated in adaptation to symbiosis. NC64A exhibits variations in GC content across its genome that correlate with global expression level, average intron size, and codon usage bias. Although Chlorella species have been assumed to be asexual and nonmotile, the NC64A genome encodes all the known meiosis-specific proteins and a subset of proteins found in flagella. We hypothesize that Chlorella might have retained a flagella-derived structure that could be involved in sexual reproduction. Furthermore, a survey of phytohormone pathways in chlorophyte algae identified algal orthologs of Arabidopsis thaliana genes involved in hormone biosynthesis and signaling, suggesting that these functions were established prior to the evolution of land plants. We show that the ability of Chlorella to produce chitinous cell walls likely resulted from the capture of metabolic genes by horizontal gene transfer from algal viruses, prokaryotes, or fungi. Analysis of the NC64A genome substantially advances our understanding of the green lineage evolution, including the genomic interplay with viruses and symbiosis between eukaryotes. |
| وصف الملف: | application/pdf |
| تدمد: | 1532-298X 1040-4651 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9082ae9b9c25a6321c050e534a375ab https://doi.org/10.1105/tpc.110.076406 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....a9082ae9b9c25a6321c050e534a375ab |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1532298X 10404651 |
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