Electrostatic Interaction-Based High Tissue Adhesive, Stretchable Microelectrode Arrays for the Electrophysiological Interface
| العنوان: | Electrostatic Interaction-Based High Tissue Adhesive, Stretchable Microelectrode Arrays for the Electrophysiological Interface |
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| المؤلفون: | Gongwei Tian, Yan Liu, Mei Yu, Cuiyuan Liang, Dan Yang, Jianping Huang, Qinyi Zhao, Wei Zhang, Jianhui Chen, Yu Wang, Ping Xu, Zhiyuan Liu, Dianpeng Qi |
| المصدر: | ACS Applied Materials & Interfaces. 14:4852-4861 |
| بيانات النشر: | American Chemical Society (ACS), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Surface Properties, Materials Testing, Static Electricity, Biocompatible Materials, Tissue Adhesives, General Materials Science, Particle Size, Microelectrodes |
| الوصف: | The drift or fall of stretchable neural microelectrodes from the surface of wet and dynamic tissues severely hampers the adoption of microelectrodes for electrophysiological signal monitoring. Endowing the stretchable electrodes with adhesive ability is an effective way to overcome these problems. Current adhesives form tough adhesion to tissues by covalent interaction, which decreases the biocompatibility of the adhesives. Here, we fabricate a strong electrostatic adhesive (noncovalent interaction), highly conformal, stretchable microelectrode arrays (MEAs) for the electrophysiological interface. This MEA was composed of polypyrrole (PPy) as the electrode material and hydrogel as the stretchable substrate [the cross-linked and copolymerized hydrogel of 2-acrylamido-2-methylpropane sulfonic acid (AMPS), gelatin, chitosan, 2-methoxyethyl acrylate, and acrylic acid is named PAGMA]. Strong and stable electrostatic adhesion (85 kPa) and high stretchability (100%) allow for the integration of PPy MEAs based on the PAGMA hydrogel substrate (PPy-PAGMA MEAs) on diverse wet dynamic tissues. Additionally, by adjusting the concentration of AMPS in PAGMA, the hydrogel (PAGMA-1) can produce tough adhesion to many inorganic and elastomer materials. Finally, the PPy-PAGMA MEAs were toughly and conformally adhered on the rat's subcutaneous muscle and beating heart, and the rat's electrophysiological signals were successfully recorded. The development of these adhesive MEAs offers a promising strategy to establish stable and compliant electrode-tissue interfaces. |
| تدمد: | 1944-8252 1944-8244 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98e4bc764daa3ce6c90903d7aaf7cd8 https://doi.org/10.1021/acsami.1c18983 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....a98e4bc764daa3ce6c90903d7aaf7cd8 |
| قاعدة البيانات: | OpenAIRE |
Find this issue from the American Chemical Society | تدمد: | 19448252 19448244 |
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