Design of a Compton camera for 3D prompt-γ imaging during ion beam therapy
| العنوان: | Design of a Compton camera for 3D prompt-γ imaging during ion beam therapy |
|---|---|
| المؤلفون: | A.H. Walenta, Marius Chevallier, M. Testa, Nicolas Freud, F. Roellinghoff, Gerard Montarou, M.-H. Richard, F. Le Foulher, Etienne Testa, Denis Dauvergne, Jean Michel Létang, Julie Constanzo, Cédric Ray, P. Henriquet |
| المساهمون: | Institut de Physique Nucléaire de Lyon (IPNL), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Controle Non Destructif par Rayonnements Ionisants (CNDRI), Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA), CAS-PHABIO, Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Laboratoire de Physique Corpusculaire - Clermont-Ferrand (LPC), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), GEANT4, Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS) |
| المصدر: | Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment Imaging 2010, International conference on imaging techniques in subatomic physics, astrophysics, medicine, biology and industry Imaging 2010, International conference on imaging techniques in subatomic physics, astrophysics, medicine, biology and industry, Jun 2010, Stockholm, Sweden. pp.s20-s23, ⟨10.1016/j.nima.2011.01.069⟩ |
| بيانات النشر: | HAL CCSD, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Nuclear and High Energy Physics, Photon, Ion beam, Point source, Physics::Instrumentation and Detectors, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, [PHYS.PHYS.PHYS-BIO-PH]Physics [physics]/Physics [physics]/Biological Physics [physics.bio-ph], Geant4, Bragg peak, 01 natural sciences, Lyso, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Optics, Hodoscope, hadrontherapy, 0103 physical sciences, prompt gamma, Instrumentation, Image resolution, Compton camera, Physics, 010308 nuclear & particles physics, business.industry, Detector, [PHYS.PHYS.PHYS-MED-PH]Physics [physics]/Physics [physics]/Medical Physics [physics.med-ph], ion beam therapy, business |
| الوصف: | We investigate, by means of Geant4 simulations, a real-time method to control the position of the Bragg peak during ion therapy, based on a Compton camera in combination with a beam tagging device (hodoscope) in order to detect the prompt gamma emitted during nuclear fragmentation. The proposed set-up consists of a stack of 2 mm thick silicon strip detectors and a LYSO absorber detector. The γ emission points are reconstructed analytically by intersecting the ion trajectories given by the beam hodoscope and the Compton cones given by the camera. The camera response to a polychromatic point source in air is analyzed with regard to both spatial resolution and detection efficiency. Various geometrical configurations of the camera have been tested. In the proposed configuration, for a typical polychromatic photon point source, the spatial resolution of the camera is about 8.3 mm FWHM and the detection efficiency 2.5×10−4 (reconstructable photons/emitted photons in 4 π ). Finally, the clinical applicability of our system is considered and possible starting points for further developments of a prototype are discussed. |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa5e9a231761f9555ecfd575c8ff29f2 http://hal.in2p3.fr/in2p3-00559943 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....aa5e9a231761f9555ecfd575c8ff29f2 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |