Do lumbar magnetic resonance imaging changes predict neuropathic pain in patients with chronic non-specific low back pain?
| العنوان: | Do lumbar magnetic resonance imaging changes predict neuropathic pain in patients with chronic non-specific low back pain? |
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| المؤلفون: | Eva Vagaská, Alexandra Litavcova, Eva Vlčková, Milos Kerkovsky, Jiri Jarkovsky, Josef Bednarik, Iva Šrotová, Blanka Adamová |
| المصدر: | Medicine |
| بيانات النشر: | Wolters Kluwer Health, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Observational Study, Logistic regression, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Lumbar, Sex Factors, medicine, Humans, 030212 general & internal medicine, Pain Measurement, neuropathic pain, Lumbar Vertebrae, medicine.diagnostic_test, business.industry, DN4, Lumbar spinal stenosis, Magnetic resonance imaging, Modic changes, General Medicine, Odds ratio, Middle Aged, medicine.disease, Prognosis, Low back pain, Magnetic Resonance Imaging, 3. Good health, Cross-Sectional Studies, 030220 oncology & carcinogenesis, Neuropathic pain, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Neuralgia, Female, Spinal Diseases, Radiology, medicine.symptom, business, Low Back Pain, Research Article |
| الوصف: | Supplemental Digital Content is available in the text The aim of this observational, cross-sectional study was to analyse lumbar magnetic resonance imaging (MRI) findings in patients with non-specific chronic low back pain (CLBP), and to evaluate any correlation with pain intensity and their capacity to predict neuropathic pain (NP) in these patients. Fifty-two patients with non-specific CLBP, between 21 and 62 years of age, 50% men, were investigated. Lumbar MRI was employed to assess disc degeneration, endplate changes, Modic changes, disc displacement, facet degeneration, foraminal stenosis and central lumbar spinal stenosis. The characteristics of pain were evaluated and patients were divided into 2 subgroups: with NP (24 patients) and without NP (28 patients), based on the results of a DN4-interview. Correlations between particular MRI changes and their relations to the intensity of pain were evaluated. Logistic regression was used to disclose predictors of NP. Lumbar spine degenerative features were frequent in patients with non-specific CLBP, with L4/5 the most affected level. A significant correlation emerged between the severity of degenerative changes in particular lumbar spine structures (correlation coefficient ranging between 0.325 and 0.573), while no correlation was found between severity of degenerative changes and pain. Multivariate logistic regression revealed only 2 independent predictors of NP – female sex (odds ratio [OR] = 11.9) and a mean pain intensity of ≥4.5 in the previous 4 weeks (OR = 13.1). Degenerative changes in the lumbar spine are frequent MRI findings, but do not correlate with the intensity of pain and do not predict NP. However, female sex and pain intensity do predict NP. |
| اللغة: | English |
| تدمد: | 1536-5964 0025-7974 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab1872f5be2d66b4501f57c19deb06ee http://europepmc.org/articles/PMC6831323 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....ab1872f5be2d66b4501f57c19deb06ee |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15365964 00257974 |
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