Effects of a short-term overfeeding with fructose or glucose in healthy young males
| العنوان: | Effects of a short-term overfeeding with fructose or glucose in healthy young males |
|---|---|
| المؤلفون: | Emilienne Tudor Ngo Sock, Luc Tappy, Kim-Anne Lê, Michael Ith, Roland Kreis, Chris Boesch |
| المصدر: | British Journal of Nutrition British Journal of Nutrition, vol. 103, no. 7, pp. 939-943 Ngo Sock, Emilienne Tudor; Lê, Kim-Anne; Ith, Michael; Kreis, Roland; Boesch, Chris; Tappy, Luc (2010). Effects of a short-term overfeeding with fructose or glucose in healthy young males. British journal of nutrition, 103(7), pp. 939-43. Cambridge: Cambridge University Press 10.1017/S0007114509992819 <http://dx.doi.org/10.1017/S0007114509992819> |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Blood Glucose, Male, medicine.medical_specialty, 030309 nutrition & dietetics, medicine.medical_treatment, Cholesterol, VLDL, Medicine (miscellaneous), Blood sugar, 030209 endocrinology & metabolism, Fructose, Biology, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, Overnutrition, 0302 clinical medicine, Dietary Sucrose, Internal medicine, medicine, Humans, Insulin, Intramyocellular lipids, Triglycerides, Pancreatic hormone, Muscle Cells, 0303 health sciences, Nutrition and Dietetics, Cholesterol, Alanine Transaminase/blood, Blood Glucose/metabolism, Cholesterol, VLDL/blood, Diet, Dietary Sucrose/administration & dosage, Energy Intake, Fasting, Fructose/administration & dosage, Glucose/administration & dosage, Insulin/blood, Lipid Metabolism, Liver/drug effects, Liver/metabolism, Muscle Cells/drug effects, Muscle Cells/metabolism, Overnutrition/metabolism, Triglycerides/blood, Alanine Transaminase, Lipid metabolism, Metabolism, Glucose, Endocrinology, Liver, chemistry |
| الوصف: | Consumption of simple carbohydrates has markedly increased over the past decades, and may be involved in the increased prevalence in metabolic diseases. Whether an increased intake of fructose is specifically related to a dysregulation of glucose and lipid metabolism remains controversial. We therefore compared the effects of hypercaloric diets enriched with fructose (HFrD) or glucose (HGlcD) in healthy men. Eleven subjects were studied in a randomised order after 7 d of the following diets: (1) weight maintenance, control diet; (2) HFrD (3·5 g fructose/kg fat-free mass (ffm) per d, +35 % energy intake); (3) HGlcD (3·5 g glucose/kg ffm per d, +35 % energy intake). Fasting hepatic glucose output (HGO) was measured with 6,6-2H2-glucose. Intrahepatocellular lipids (IHCL) and intramyocellular lipids (IMCL) were measured by1H magnetic resonance spectroscopy. Both fructose and glucose increased fasting VLDL-TAG (HFrD: +59 %,P P = 0·11) and IHCL (HFrD: +52 %,P P = 0·06). HGO increased after both diets (HFrD: +5 %,P P = 0·05). No change was observed in fasting glycaemia, insulin and alanine aminotransferase concentrations. IMCL increased significantly only after the HGlcD (HFrD: +24 %, NS; HGlcD: +59 %,P |
| وصف الملف: | application/pdf |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf888bf2016ed0212494ff4f16f61f4 http://doc.rero.ch/record/298428/files/S0007114509992819.pdf |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....abf888bf2016ed0212494ff4f16f61f4 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |