Effects of Stratified Vitamin D Supplementation in Middle-Aged and Elderly Individuals with Vitamin D Insufficiency
| العنوان: | Effects of Stratified Vitamin D Supplementation in Middle-Aged and Elderly Individuals with Vitamin D Insufficiency |
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| المؤلفون: | Xinyu Miao, Lili Zhang, Minyan Liu, Shuangtong Yan, Yanhui Lu, Xiaoling Cheng, Banruo Sun, Chunlin Li, Xiaomin Fu, Nan Li |
| المصدر: | Hormone and Metabolic Research. 50:747-753 |
| بيانات النشر: | Georg Thieme Verlag KG, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, 030209 endocrinology & metabolism, Intervention group, Biochemistry, Gastroenterology, vitamin D deficiency, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Internal medicine, medicine, Vitamin D and neurology, Humans, Elderly people, 030212 general & internal medicine, Vitamin D, Life Style, Aged, Vitamin d supplementation, business.industry, Life style, Incidence (epidemiology), Biochemistry (medical), General Medicine, Middle Aged, Vitamin D Deficiency, medicine.disease, Dietary Supplements, Oral vitamin, Female, business |
| الوصف: | The incidence of vitamin D deficiency is high globally, and vitamin D supplementation draws particular attention. The objective of this study was to investigate the effects of stratified vitamin D supplementation in middle-aged and elderly individuals with vitamin D insufficiency in Beijing. A total of 448 subjects aged over 40 years old were selected from a community in Beijing. Among them, 100 middle-aged and elderly people with vitamin D insufficiency were randomly selected on a voluntary basis. They were further divided into control group and intervention group. The control group received health education and lifestyle guidance, and the intervention group received lifestyle guidance and vitamin D supplementation for nine months. The doses were stratified as follows: for vitamin D insufficiency, oral vitamin D3 supplement was given at 5000 IU/w; for mild vitamin D deficiency, oral vitamin D3 supplement was given at 10 000 IU/w; for severe vitamin D deficiency, oral vitamin D3 supplement was given at 15 000 IU/w. Safety evaluation was conducted after three-month treatment. The intervention group consisted of 8%, 62%, and 30% of cases who had vitamin D insufficiency, mild vitamin D deficiency, and severe vitamin D deficiency, respectively, which were similar with the control group. It showed that the blood 25(OH)D level increased significantly in the intervention group, from 14.30±4.30 ng/ml to 33.62±6.99 ng/ml (p |
| تدمد: | 1439-4286 0018-5043 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7c859146a87e9444cc4e2d0ae37f55 https://doi.org/10.1055/a-0746-5031 |
| رقم الأكسشن: | edsair.doi.dedup.....ac7c859146a87e9444cc4e2d0ae37f55 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14394286 00185043 |
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