التفاصيل البيبلوغرافية
العنوان:
Clinical characteristics and outcomes according to age in lenalidomide-treated patients with RBC transfusion-dependent lower-risk MDS and del(5q)
المؤلفون:
Petra Muus , Alan F. List , Barry S. Skikne , Pierre Fenaux , Stephen D. Nimer , Bayard L. Powell , Xujie Yu , Dominik Selleslag , Moshe Mittelman , Jamile M. Shammo , Agnès Guerci-Bresler , Peter L. Greenberg , Consuelo del Cañizo , H. Joachim Deeg , Mikkael A. Sekeres , Odile Beyne-Rauzy , Eva Hellström-Lindberg , Aristoteles Giagounidis
المصدر:
Journal of Hematology & Oncology, 10, 131
سنة النشر:
2017
مصطلحات موضوعية:
Male , Cancer Research , Vascular damage Radboud Institute for Health Sciences [Radboudumc 16] , 0302 clinical medicine , Risk Factors , hemic and lymphatic diseases , del(5q) , Lenalidomide , Aged, 80 and over , Rbc transfusion , Hematology , Age Factors , Myeloid leukemia , lcsh:Diseases of the blood and blood-forming organs , Middle Aged , Prognosis , lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens , Thalidomide , Leukemia, Myeloid, Acute , Treatment Outcome , Oncology , International Prognostic Scoring System , 030220 oncology & carcinogenesis , Disease Progression , Chromosomes, Human, Pair 5 , Female , Disease characteristics , Erythrocyte Transfusion , medicine.drug , Adult , medicine.medical_specialty , Myelodysplastic syndromes , Lower risk , lcsh:RC254-282 , Cytogenetics , 03 medical and health sciences , Age , Internal medicine , medicine , Humans , Immunologic Factors , Molecular Biology , Aged , Acute myeloid leukemia , lcsh:RC633-647.5 , business.industry , Research , medicine.disease , Immunology , business , 030215 immunology
الوصف:
Background Particularly since the advent of lenalidomide, lower-risk myelodysplastic syndromes (MDS) patients with del(5q) have been the focus of many studies; however, the impact of age on disease characteristics and response to lenalidomide has not been analyzed. Methods We assessed the effect of age on clinical characteristics and outcomes in 286 lenalidomide-treated MDS patients with del(5q) from two multicenter trials. Results A total of 33.9, 34.3, and 31.8% patients were aged
وصف الملف:
application/pdf
تدمد:
1756-8722
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb051b0d2e4977d57274e0390ac8308 https://hdl.handle.net/2066/175140
حقوق:
OPEN
رقم الأكسشن:
edsair.doi.dedup.....acb051b0d2e4977d57274e0390ac8308
قاعدة البيانات:
OpenAIRE
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